H3-3A H3.3 histone A [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: H3-3Aprovided by VGNC
Official Full Name: H3.3 histone Aprovided by VGNC
Primary source: VGNC:VGNC:83611
See related: Ensembl:ENSBTAG00000024561
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: H3-3B; H3F3A
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	16	NC_037343.1 (29079663..29087863)

Chromosome 16 - NC_037343.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037343.1 Chromosome 16 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

H3F3A mRNA abundance is stable whereas H3F3B and HIRA mRNA are relatively dynamic during early embryonic development. H3F3B mRNA quantity is also considerably higher than H3F3A. Immunofluorescence analysis revealed an even distribution of H3.3 between paternal and maternal pronuclei in zygotes, and subsequent stage-specific localization of H3.3 in early bovine embryos.
Title: Characterization of H3.3 and HIRA expression and function in bovine early embryos.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

H3f3a (e-PCR), detects polymorphism
- UniSTS:525689

WI-6046 (e-PCR)
- UniSTS:73465

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein heterodimerization activity	IEA Inferred from Electronic Annotation more info	PubMed
enables structural constituent of chromatin	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of nucleosome	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: histone H3.3

Names: H3 histone, family 3A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.