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    Ccdc169 coiled-coil domain containing 169 [ Mus musculus (house mouse) ]

    Gene ID: 320604, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Ccdc169provided by MGI
    Official Full Name
    coiled-coil domain containing 169provided by MGI
    Primary source
    MGI:MGI:2444356
    See related
    Ensembl:ENSMUSG00000048655 AllianceGenome:MGI:2444356
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    A730037C10Rik
    Summary
    Orthologous to human CCDC169 (coiled-coil domain containing 169). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in testis adult (RPKM 8.5) and liver E14 (RPKM 1.2) See more
    Orthologs
    human all
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    Genomic context

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    See Ccdc169 in Genome Data Viewer
    Location:
    3 C; 3 26.53 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (55044760..55082671)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (55137339..55175250)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4931419H13 gene Neighboring gene STARR-seq mESC enhancer starr_07692 Neighboring gene cyclin A1 Neighboring gene STARR-seq mESC enhancer starr_07693 Neighboring gene STARR-seq mESC enhancer starr_07694 Neighboring gene spartin Neighboring gene spermatogenesis and oogenesis specific basic helix-loop-helix 2 Neighboring gene STARR-seq mESC enhancer starr_07696 Neighboring gene doublecortin-like kinase 1 Neighboring gene predicted gene, 25132

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    2. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    3. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    4. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article
    5. Functional annotation of a full-length mouse cDNA collection. Kawai J, et al. Nature, 2001 Feb 8. PMID 11217851

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 169

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001290138.1 → NP_001277067.1  coiled-coil domain-containing protein 169 isoform b

      See identical proteins and their annotated locations for NP_001277067.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains an alternate 5' terminal exon, and it thus differs in the 5' UTR and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) is shorter at the N-terminus, compared to isoform a. Both variants 2 and 3 encode isoform b.
      Source sequence(s)
      AC111132, AI467609, AK042903
      Consensus CDS
      CCDS79907.1
      UniProtKB/Swiss-Prot
      Q8BXX9
      Related
      ENSMUSP00000049698.5, ENSMUST00000052904.11
      Conserved Domains (1) summary
      pfam15372
      Location:1 → 99
      DUF4600; Domain of unknown function (DUF4600)

    2. NM_001290141.1 → NP_001277070.1  coiled-coil domain-containing protein 169 isoform b

      See identical proteins and their annotated locations for NP_001277070.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) contains an alternate 5' terminal exon, and it thus differs in the 5' UTR and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) is shorter at the N-terminus, compared to isoform a. Both variants 2 and 3 encode isoform b.
      Source sequence(s)
      AC111132, AI467609, AK042903, AK076919
      Consensus CDS
      CCDS79907.1
      UniProtKB/Swiss-Prot
      Q8BXX9
      Conserved Domains (1) summary
      pfam15372
      Location:1 → 99
      DUF4600; Domain of unknown function (DUF4600)

    3. NM_177203.3 → NP_796177.2  coiled-coil domain-containing protein 169 isoform a

      See identical proteins and their annotated locations for NP_796177.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (a).
      Source sequence(s)
      AI467609, AK042903, AK076919
      Consensus CDS
      CCDS17357.2
      UniProtKB/Swiss-Prot
      Q8BVQ6, Q8BXX9
      UniProtKB/TrEMBL
      D3YWT6
      Related
      ENSMUSP00000054771.8, ENSMUST00000061099.14
      Conserved Domains (1) summary
      pfam15372
      Location:55 → 181
      DUF4600; Domain of unknown function (DUF4600)

    RNA

    1. NR_110776.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) contains an additional internal exon in the 3' region, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC111132, AI467609, AK042903, AK076919

    2. NR_110780.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) lacks an exon in the 5' region and includes an additional internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AI467609, AK042903, AK076919, BC171976

    3. NR_110781.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) lacks an exon in the 5' region and includes two additional internal exons, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AI467609, AK042903, AK076919, BC171978

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      55044760..55082671
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006501572.5 → XP_006501635.1  coiled-coil domain-containing protein 169 isoform X2

      UniProtKB/TrEMBL
      D3YWT6
      Related
      ENSMUSP00000112414.3, ENSMUST00000118963.9
      Conserved Domains (1) summary
      pfam15372
      Location:55 → 181
      DUF4600; Domain of unknown function (DUF4600)

    2. XM_006501571.5 → XP_006501634.1  coiled-coil domain-containing protein 169 isoform X1

      UniProtKB/TrEMBL
      D3YWT6
      Conserved Domains (1) summary
      pfam15372
      Location:55 → 181
      DUF4600; Domain of unknown function (DUF4600)

    3. XM_017319613.2 → XP_017175102.1  coiled-coil domain-containing protein 169 isoform X3

      UniProtKB/Swiss-Prot
      Q8BXX9
      Conserved Domains (1) summary
      pfam15372
      Location:1 → 99
      DUF4600; Domain of unknown function (DUF4600)

    4. XM_017319614.2 → XP_017175103.1  coiled-coil domain-containing protein 169 isoform X3

      UniProtKB/Swiss-Prot
      Q8BXX9
      Conserved Domains (1) summary
      pfam15372
      Location:1 → 99
      DUF4600; Domain of unknown function (DUF4600)

    5. XM_006501575.3 → XP_006501638.1  coiled-coil domain-containing protein 169 isoform X3

      See identical proteins and their annotated locations for XP_006501638.1

      UniProtKB/Swiss-Prot
      Q8BXX9
      Conserved Domains (1) summary
      pfam15372
      Location:1 → 99
      DUF4600; Domain of unknown function (DUF4600)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BXX9.2 GenPept UniProtKB/Swiss-Prot:Q8BXX9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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