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    Taar8b trace amine-associated receptor 8B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 319106, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Taar8bprovided by RGD
    Official Full Name
    trace amine-associated receptor 8Bprovided by RGD
    Primary source
    RGD:631386
    See related
    EnsemblRapid:ENSRNOG00000062917 AllianceGenome:RGD:631386
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ta7
    Summary
    Predicted to enable trace-amine receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane. Orthologous to human TAAR8 (trace amine associated receptor 8). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Testes (RPKM 18.5), Thymus (RPKM 2.1) and 1 other tissue See more
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    Genomic context

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    See Taar8b in Genome Data Viewer
    Location:
    1p12
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (23122214..23126739)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (21302978..21307489)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (23565350..23568888)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene trace amine-associated receptor 9 Neighboring gene trace amine-associated receptor 8C Neighboring gene trace amine associated receptor 8A Neighboring gene trace amine associated receptor 7i, pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Trace amines: identification of a family of mammalian G protein-coupled receptors. Borowsky B, et al. Proc Natl Acad Sci U S A, 2001 Jul 31. PMID 11459929, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables trace-amine receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    trace amine-associated receptor 8b
    Names
    taR-7
    taR-8b
    trace amine receptor 7
    trace amine receptor 8b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175601.1 → NP_783191.1  trace amine-associated receptor 8b

      See identical proteins and their annotated locations for NP_783191.1

      Status: PROVISIONAL

      Source sequence(s)
      AF380195
      UniProtKB/Swiss-Prot
      Q923X9, Q923Y3
      Conserved Domains (2) summary
      pfam00001
      Location:48 → 312
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:42 → 327
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      23122214..23126739
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006227719.5 → XP_006227781.1  trace amine-associated receptor 8b isoform X2

      See identical proteins and their annotated locations for XP_006227781.1

      UniProtKB/Swiss-Prot
      Q923X9
      UniProtKB/TrEMBL
      A6JUL7
      Related
      ENSRNOP00000044110.4, ENSRNOT00000043157.4
      Conserved Domains (2) summary
      pfam00001
      Location:63 → 327
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:57 → 342
      7tm_4; Olfactory receptor

    2. XM_063265674.1 → XP_063121744.1  trace amine-associated receptor 8b isoform X1

    3. XM_017589310.2 → XP_017444799.1  trace amine-associated receptor 8b isoform X3

      UniProtKB/Swiss-Prot
      Q923X9, Q923Y3
      Related
      ENSRNOP00000101737.1, ENSRNOT00000173053.1
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q923Y3.1 GenPept UniProtKB/Swiss-Prot:Q923Y3

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