Taar8a trace amine associated receptor 8A [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Taar8aprovided by RGD
Full Name: trace amine associated receptor 8Aprovided by RGD
Primary source: RGD:631391
See related: EnsemblRapid:ENSRNOG00000070320 AllianceGenome:RGD:631391
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Ta11; Trar5
Summary: Predicted to enable trace-amine receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Orthologous to human TAAR8 (trace amine associated receptor 8). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

Location:: 1p12

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (23152013..23153137, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (21332763..21333887, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (22364551..22365675)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data show that TAARs were expressed only at trace amounts in most of the tissues, the exceptions being TAAR1 in stomach and testis and TAAR8a in intestine, spleen, and testis.
Title: Distribution of exogenous [125I]-3-iodothyronamine in mouse in vivo: relationship with trace amine-associated receptors.

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General gene information

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Markers

Taar8a (e-PCR), detects polymorphism
- UniSTS:516842

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables trace-amine receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables trace-amine receptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: trace amine-associated receptor 8a

Names: taR-11; taR-8a; trace amine receptor 11; trace amine receptor 5; trace amine receptor 8a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_175599.1 → NP_783189.1 trace amine-associated receptor 8a

See identical proteins and their annotated locations for NP_783189.1

Status: PROVISIONAL

Source sequence(s)

AF380199

UniProtKB/Swiss-Prot

Q923X9

UniProtKB/TrEMBL

A0A0G2JSU5, A6JUL8

Related

ENSRNOP00000040109.1, ENSRNOT00000044098.3

Conserved Domains (2) summary

pfam00001
Location:78 → 342

7tm_1; 7 transmembrane receptor (rhodopsin family)

cl21561
Location:72 → 357

7tm_4; Olfactory receptor