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    Saxol1 stabilizer of axonemal microtubules like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 317471, updated on 2-Nov-2024

    Summary

    Official Symbol
    Saxol1provided by RGD
    Official Full Name
    stabilizer of axonemal microtubules like 1provided by RGD
    Primary source
    RGD:1549779
    See related
    AllianceGenome:RGD:1549779
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Saxo1; Fam154a
    Summary
    Predicted to enable microtubule binding activity. Predicted to be involved in several processes, including cold acclimation; positive regulation of cilium assembly; and protein stabilization. Predicted to be located in motile cilium. Predicted to be active in microtubule cytoskeleton and sperm flagellum. Orthologous to human SAXO1 (stabilizer of axonemal microtubules 1). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See Saxol1 in Genome Data Viewer
    Location:
    Xq13
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (31605096..31607253)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (27973442..27975599)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (29520263..29522420)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene EGF-like-domain, multiple 6 Neighboring gene transcription elongation factor A N-terminal and central domain containing Neighboring gene RAB9A, member RAS oncogene family Neighboring gene trafficking protein particle complex subunit 2 Neighboring gene Ofd1 centriole and centriolar satellite protein

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables microtubule binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in cell projection organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cellular response to cold ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in cold acclimation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of cilium assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein stabilization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in axonemal microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in axonemal microtubule ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in centriole IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in centriole ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in ciliary basal body ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in motile cilium ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in sperm flagellum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in sperm flagellum ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    stabilizer of axonemal microtubules 1
    Names
    protein FAM154A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014112.2NP_001014134.2  stabilizer of axonemal microtubules 1

      Status: VALIDATED

      Source sequence(s)
      BC078965
      UniProtKB/Swiss-Prot
      Q6AYP6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      31605096..31607253
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)