U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    Xylb xylulokinase [ Rattus norvegicus (Norway rat) ]

    Gene ID: 316067, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Xylbprovided by RGD
    Official Full Name
    xylulokinaseprovided by RGD
    Primary source
    RGD:1307372
    See related
    EnsemblRapid:ENSRNOG00000014168 AllianceGenome:RGD:1307372
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable xylulokinase activity. Predicted to be involved in phosphorylation and xylulose metabolic process. Predicted to be active in cytosol. Orthologous to human XYLB (xylulokinase). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 427.5), Liver (RPKM 248.5) and 2 other tissues See more
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    8q32
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (127971194..128012511)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (119093466..119128858)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (128041875..128076951)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene oxidative stress responsive kinase 1 Neighboring gene uncharacterized LOC120094290 Neighboring gene MYD88, innate immune signal transduction adaptor Neighboring gene acetyl-CoA acyltransferase 1A Neighboring gene activin A receptor type 2B Neighboring gene 40S ribosomal protein S27-like

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Structure and function of human xylulokinase, an enzyme with important roles in carbohydrate metabolism. Bunker RD, et al. J Biol Chem, 2013 Jan 18. PMID 23179721, Free PMC Article
    2. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • MGC124790

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables D-xylulokinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables D-xylulokinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables D-xylulokinase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables D-xylulokinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in D-xylose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in carbohydrate phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in xylulose metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in xylulose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in xylulose metabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in xylulose metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    xylulose kinase
    Names
    xylulokinase homolog (H. influenzae)
    NP_001028876.2
    XP_006244158.1
    XP_017451187.2
    XP_017451188.2
    XP_038937568.1
    XP_038937572.1
    XP_063121726.1
    XP_063121727.1
    XP_063121728.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033704.2 → NP_001028876.2  xylulose kinase

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/Swiss-Prot
      Q3MIF4
      UniProtKB/TrEMBL
      A0A8I5Y795
      Related
      ENSRNOP00000092265.1, ENSRNOT00000120248.2
      Conserved Domains (1) summary
      cd07776
      Location:9 → 479
      FGGY_D-XK_euk; eukaryotic D-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      127971194..128012511
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039081644.2 → XP_038937572.1  xylulose kinase isoform X7

      Conserved Domains (1) summary
      cl17037
      Location:136 → 343
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    2. XM_063265656.1 → XP_063121726.1  xylulose kinase isoform X2

    3. XM_017595699.3 → XP_017451188.2  xylulose kinase isoform X4

      Conserved Domains (1) summary
      cd07776
      Location:136 → 583
      FGGY_D-XK_euk; eukaryotic D-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases

    4. XM_017595698.3 → XP_017451187.2  xylulose kinase isoform X3

      UniProtKB/TrEMBL
      G3V7T5
      Related
      ENSRNOP00000019106.9, ENSRNOT00000019106.9
      Conserved Domains (1) summary
      cd07776
      Location:136 → 606
      FGGY_D-XK_euk; eukaryotic D-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases

    5. XM_039081640.2 → XP_038937568.1  xylulose kinase isoform X1

      UniProtKB/Swiss-Prot
      Q3MIF4
      Related
      ENSRNOP00000112660.1, ENSRNOT00000153110.1
      Conserved Domains (1) summary
      cd07776
      Location:136 → 606
      FGGY_D-XK_euk; eukaryotic D-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases

    6. XM_063265658.1 → XP_063121728.1  xylulose kinase isoform X5

      UniProtKB/Swiss-Prot
      Q3MIF4
      UniProtKB/TrEMBL
      A6I3W3

    7. XM_063265657.1 → XP_063121727.1  xylulose kinase isoform X5

      UniProtKB/Swiss-Prot
      Q3MIF4
      UniProtKB/TrEMBL
      A6I3W3

    8. XM_006244096.4 → XP_006244158.1  xylulose kinase isoform X6

      UniProtKB/Swiss-Prot
      Q3MIF4
      Conserved Domains (2) summary
      PLN02669
      Location:1 → 452
      PLN02669; xylulokinase
      cd07776
      Location:1 → 401
      FGGY_D-XK_euk; eukaryotic D-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases

    RNA

    1. XR_356707.5 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3MIF4.1 GenPept UniProtKB/Swiss-Prot:Q3MIF4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous