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    Vsig1 V-set and immunoglobulin domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 315920, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Vsig1provided by RGD
    Official Full Name
    V-set and immunoglobulin domain containing 1provided by RGD
    Primary source
    RGD:1565570
    See related
    EnsemblRapid:ENSRNOG00000054219 AllianceGenome:RGD:1565570
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in maintenance of gastrointestinal epithelium. Predicted to act upstream of or within epithelial cell morphogenesis. Predicted to be located in plasma membrane. Predicted to be active in basolateral plasma membrane. Orthologous to human VSIG1 (V-set and immunoglobulin domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Testes (RPKM 44.3), Uterus (RPKM 4.5) and 1 other tissue See more
    Orthologs
    human mouse all
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    Genomic context

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    See Vsig1 in Genome Data Viewer
    Location:
    Xq33
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (109395406..109428612)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (104607031..104640128)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (112268786..112303849)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103694504 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene testis expressed 13B Neighboring gene proteasome 26S subunit, non-ATPase 10 Neighboring gene autophagy related 4A, cysteine peptidase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Adhesion protein VSIG1 is required for the proper differentiation of glandular gastric epithelia. Oidovsambuu O, et al. PLoS One, 2011. PMID 21991385, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC114516

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in epithelial cell morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within epithelial cell morphogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in maintenance of gastrointestinal epithelium IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in maintenance of gastrointestinal epithelium IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within maintenance of gastrointestinal epithelium ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in basolateral plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in basolateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    V-set and immunoglobulin domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037784.1 → NP_001032873.1  V-set and immunoglobulin domain-containing protein 1 precursor

      See identical proteins and their annotated locations for NP_001032873.1

      Status: PROVISIONAL

      Source sequence(s)
      BC098943
      UniProtKB/Swiss-Prot
      Q4KLY3
      UniProtKB/TrEMBL
      A6HLR1
      Related
      ENSRNOP00000075185.1, ENSRNOT00000082652.3
      Conserved Domains (3) summary
      pfam05887
      Location:315 → 404
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      smart00410
      Location:153 → 228
      IG_like; Immunoglobulin like
      cl11960
      Location:25 → 128
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      109395406..109428612
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006234243.5 → XP_006234305.1  V-set and immunoglobulin domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K4G7
      Related
      ENSRNOP00000073037.1, ENSRNOT00000091441.3
      Conserved Domains (3) summary
      pfam05887
      Location:351 → 440
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      smart00410
      Location:189 → 264
      IG_like; Immunoglobulin like
      cl11960
      Location:25 → 164
      Ig; Immunoglobulin domain

    2. XM_006234245.5 → XP_006234307.1  V-set and immunoglobulin domain-containing protein 1 isoform X2

      See identical proteins and their annotated locations for XP_006234307.1

      Conserved Domains (3) summary
      cd00096
      Location:52 → 119
      Ig; Immunoglobulin domain
      smart00410
      Location:47 → 122
      IG_like; Immunoglobulin like
      cl11960
      Location:1 → 22
      Ig; Immunoglobulin domain

    3. XM_006234246.5 → XP_006234308.1  V-set and immunoglobulin domain-containing protein 1 isoform X2

      See identical proteins and their annotated locations for XP_006234308.1

      Conserved Domains (3) summary
      cd00096
      Location:52 → 119
      Ig; Immunoglobulin domain
      smart00410
      Location:47 → 122
      IG_like; Immunoglobulin like
      cl11960
      Location:1 → 22
      Ig; Immunoglobulin domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4KLY3.1 GenPept UniProtKB/Swiss-Prot:Q4KLY3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools