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    Tmem45b transmembrane protein 45b [ Rattus norvegicus (Norway rat) ]

    Gene ID: 315524, updated on 2-Nov-2024

    Summary

    Official Symbol
    Tmem45bprovided by RGD
    Official Full Name
    transmembrane protein 45bprovided by RGD
    Primary source
    RGD:1305586
    See related
    EnsemblRapid:ENSRNOG00000008515 AllianceGenome:RGD:1305586
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305586
    Summary
    Predicted to be involved in innate immune response. Predicted to be located in Golgi apparatus; endosome membrane; and lysosomal membrane. Orthologous to human TMEM45B (transmembrane protein 45B). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 50.0), Thymus (RPKM 21.8) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Tmem45b in Genome Data Viewer
    Location:
    8q13
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (38123423..38168599, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (29865276..29910453, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (32563872..32609212, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene PR/SET domain 10 Neighboring gene ribosomal protein L32 like 1 Neighboring gene nuclear factor related to kappa B binding protein Neighboring gene uncharacterized LOC134480011 Neighboring gene large ribosomal subunit protein eL21-like Neighboring gene S-adenosylmethionine decarboxylase 2 like, pseudogene 1 Neighboring gene phosphoribosyl pyrophosphate synthetase 1, pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC124767

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endosome membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in lysosomal membrane IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033067.2NP_001028239.1  transmembrane protein 45B

      See identical proteins and their annotated locations for NP_001028239.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/Swiss-Prot
      Q497B2
      UniProtKB/TrEMBL
      A6JYG6
      Related
      ENSRNOP00000011329.4, ENSRNOT00000011329.6
      Conserved Domains (1) summary
      pfam04819
      Location:120237
      DUF716; Family of unknown function (DUF716)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      38123423..38168599 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)