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    Slc7a13 solute carrier family 7 member 13 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 313089, updated on 2-Nov-2024

    Summary

    Official Symbol
    Slc7a13provided by RGD
    Official Full Name
    solute carrier family 7 member 13provided by RGD
    Primary source
    RGD:1311633
    See related
    EnsemblRapid:ENSRNOG00000024903 AllianceGenome:RGD:1311633
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable L-amino acid transmembrane transporter activity and protein heterodimerization activity. Predicted to be involved in L-cystine transport; L-glutamate transmembrane transport; and aspartate transmembrane transport. Predicted to be active in apical plasma membrane. Orthologous to human SLC7A13 (solute carrier family 7 member 13). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward (RPKM 6978.7) See more
    Orthologs
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    Genomic context

    See Slc7a13 in Genome Data Viewer
    Location:
    5q13
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (38074171..38096856)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (33277400..33298186)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (33784757..33805446)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene WW domain containing E3 ubiquitin protein ligase 1 Neighboring gene uncharacterized LOC134478942 Neighboring gene 60S ribosomal protein L13 pseudogene Neighboring gene ATPase H+ transporting V0 subunit D2 Neighboring gene alpha tocopherol transfer protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables L-amino acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables antiporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein heterodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in L-cystine transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in L-glutamate transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in amino acid transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in aspartate transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    solute carrier family 7 member 13
    Names
    sodium-independent aspartate/glutamate transporter 1
    solute carrier family 7 (anionic amino acid transporter), member 13
    solute carrier family 7, (cationic amino acid transporter, y+ system) member 13

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012100.2NP_001012100.1  solute carrier family 7 member 13

      See identical proteins and their annotated locations for NP_001012100.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/Swiss-Prot
      Q5RKI7
      UniProtKB/TrEMBL
      A6IID1
      Related
      ENSRNOP00000032751.4, ENSRNOT00000035685.8
      Conserved Domains (1) summary
      COG0531
      Location:11454
      PotE; Amino acid transporter [Amino acid transport and metabolism]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      38074171..38096856
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063287581.1XP_063143651.1  solute carrier family 7 member 13 isoform X1