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    Cog6 component of oligomeric golgi complex 6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 310411, updated on 2-Nov-2024

    Summary

    Official Symbol
    Cog6provided by RGD
    Official Full Name
    component of oligomeric golgi complex 6provided by RGD
    Primary source
    RGD:1303283
    See related
    EnsemblRapid:ENSRNOG00000013660 AllianceGenome:RGD:1303283
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in Golgi organization; glycosylation; and retrograde transport, vesicle recycling within Golgi. Predicted to be located in Golgi membrane. Predicted to be part of Golgi transport complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIl. Orthologous to human COG6 (component of oligomeric golgi complex 6). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Testes (RPKM 313.7), Heart (RPKM 123.4) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Cog6 in Genome Data Viewer
    Location:
    2q26
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (139212459..139249505, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (137062127..137099176, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (142197566..142235054, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102547111 Neighboring gene uncharacterized LOC134485913 Neighboring gene uncharacterized LOC120100818 Neighboring gene LHFPL tetraspan subfamily member 6 Neighboring gene uncharacterized LOC120100819 Neighboring gene uncharacterized LOC134485911

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC94990

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in Golgi organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in Golgi organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in glycosylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in glycosylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in glycosylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in intra-Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intra-Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in retrograde transport, vesicle recycling within Golgi IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in retrograde transport, vesicle recycling within Golgi ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of Golgi transport complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of Golgi transport complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of Golgi transport complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    conserved oligomeric Golgi complex subunit 6
    Names
    COG complex subunit 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004262.1NP_001004262.1  conserved oligomeric Golgi complex subunit 6

      See identical proteins and their annotated locations for NP_001004262.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079442
      UniProtKB/Swiss-Prot
      Q68FP9
      UniProtKB/TrEMBL
      A0A8I6G9T5
      Related
      ENSRNOP00000079046.1, ENSRNOT00000098369.2
      Conserved Domains (1) summary
      smart01087
      Location:68656
      COG6; Conserved oligomeric complex COG6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      139212459..139249505 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)