Drc12 dynein regulatory complex subunit 12 homolog [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Drc12provided by RGD
Official Full Name: dynein regulatory complex subunit 12 homologprovided by RGD
Primary source: RGD:1305351
See related: EnsemblRapid:ENSRNOG00000039086 AllianceGenome:RGD:1305351
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Ccdc153; RGD1305351
Summary: Predicted to enable identical protein binding activity. Predicted to be located in cytoplasm; cytoskeleton; and motile cilium. Orthologous to human DRC12 (dynein regulatory complex subunit 12 homolog). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Lung (RPKM 66.4) and Brain (RPKM 7.9) See more
Orthologs: human mouse all
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Genomic context

Location:: 8q22

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (53468344..53481168)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (44576528..44584345)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (48570718..48577856)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables identical protein binding	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in motile cilium	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: dynein regulatory complex protein 12; coiled-coil domain-containing protein 153

Names: coiled-coil domain containing 153

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001013953.1 → NP_001013975.1 dynein regulatory complex protein 12

Status: PROVISIONAL

Source sequence(s)

BC089910

UniProtKB/Swiss-Prot

Q5FVL4

UniProtKB/TrEMBL

A6J3W3

Related

ENSRNOP00000056528.3, ENSRNOT00000059776.4

Conserved Domains (1) summary

TIGR02168
Location:28 → 176

SMC_prok_B; chromosome segregation protein SMC, common bacterial type

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086026.1 Reference GRCr8

Range

53468344..53481168

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039081050.2 → XP_038936978.1 coiled-coil domain-containing protein 153 isoform X3

Conserved Domains (1) summary

pfam14817
Location:51 → 155

HAUS5; HAUS augmin-like complex subunit 5
XM_063265104.1 → XP_063121174.1 coiled-coil domain-containing protein 153 isoform X1

UniProtKB/Swiss-Prot

Q5FVL4
XM_063265105.1 → XP_063121175.1 coiled-coil domain-containing protein 153 isoform X3
XM_006242913.5 → XP_006242975.1 coiled-coil domain-containing protein 153 isoform X1

UniProtKB/Swiss-Prot

Q5FVL4

UniProtKB/TrEMBL

A6J3W3

Conserved Domains (1) summary

TIGR02168
Location:28 → 176

SMC_prok_B; chromosome segregation protein SMC, common bacterial type
XM_039081049.2 → XP_038936977.1 coiled-coil domain-containing protein 153 isoform X2

Conserved Domains (1) summary

PRK04863
Location:38 → 140

mukB; chromosome partition protein MukB