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    Alg13l1 ALG13, UDP-N-acetylglucosaminyltransferase subunit like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 300284, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Alg13l1provided by RGD
    Official Full Name
    ALG13, UDP-N-acetylglucosaminyltransferase subunit like 1provided by RGD
    Primary source
    RGD:1359416
    See related
    EnsemblRapid:ENSRNOG00000065758 AllianceGenome:RGD:1359416
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity. Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process. Predicted to act upstream of with a positive effect on protein N-linked glycosylation. Predicted to be part of UDP-N-acetylglucosamine transferase complex. Predicted to be active in cytoplasmic side of endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 36. Orthologous to human ALG13 (ALG13 UDP-N-acetylglucosaminyltransferase subunit). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Thymus (RPKM 77.6), Kidney (RPKM 69.5) and 9 other tissues See more
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    Genomic context

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    See Alg13l1 in Genome Data Viewer
    Location:
    Xq34
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (112681707..112702932)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (107885039..107906264)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (115561329..115589792)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein lateral stalk subunit P0, pseudogene 10 Neighboring gene ribosomal protein S26 like 5 Neighboring gene ALG13, UDP-N-acetylglucosaminyltransferase subunit Neighboring gene transient receptor potential cation channel, subfamily C, member 5 Neighboring gene U2 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in dolichol-linked oligosaccharide biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_positive_effect protein N-linked glycosylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    part_of UDP-N-acetylglucosamine transferase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in cytoplasmic side of endoplasmic reticulum membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    UDP-N-acetylglucosamine transferase subunit ALG13; UDP-N-acetylglucosamine transferase subunit ALG13 homolog
    Names
    asparagine-linked glycosylation 13 homolog
    glycosyltransferase 28 domain-containing protein 1
    NP_001013973.1
    XP_017457442.1
    XP_063135953.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013951.1 → NP_001013973.1  UDP-N-acetylglucosamine transferase subunit ALG13

      See identical proteins and their annotated locations for NP_001013973.1

      Status: PROVISIONAL

      Source sequence(s)
      BC088233
      UniProtKB/Swiss-Prot
      Q5I0K7
      UniProtKB/TrEMBL
      A6KG91
      Related
      ENSRNOP00000068463.2, ENSRNOT00000076680.4
      Conserved Domains (1) summary
      cl10013
      Location:5 → 120
      Glycosyltransferase_GTB-type; glycosyltransferase family 1 and related proteins with GTB topology

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      112681707..112702932
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017601953.3 → XP_017457442.1  UDP-N-acetylglucosamine transferase subunit ALG13 homolog isoform X1

      UniProtKB/TrEMBL
      A0A096MJN3

    2. XM_063279883.1 → XP_063135953.1  UDP-N-acetylglucosamine transferase subunit ALG13 homolog isoform X2

      UniProtKB/TrEMBL
      A6KG92
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5I0K7.1 GenPept UniProtKB/Swiss-Prot:Q5I0K7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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