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    Fam221b family with sequence similarity 221, member B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298398, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Fam221bprovided by RGD
    Official Full Name
    family with sequence similarity 221, member Bprovided by RGD
    Primary source
    RGD:1310425
    See related
    EnsemblRapid:ENSRNOG00000025453 AllianceGenome:RGD:1310425
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Orthologous to human FAM221B (family with sequence similarity 221 member B). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward (RPKM 248.4) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Fam221b in Genome Data Viewer
    Location:
    5q22
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (62706118..62715339, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (57910346..57919562, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (59156079..59165440, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene sperm associated antigen 8 Neighboring gene histidine triad nucleotide binding protein 2 Neighboring gene transmembrane protein 8B Neighboring gene olfactory receptor family 13 subfamily E member 8 Neighboring gene olfactory receptor family 13 subfamily J member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    protein FAM221B
    Names
    uncharacterized protein C9orf128 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013934.2 → NP_001013956.2  protein FAM221B

      Status: VALIDATED

      Source sequence(s)
      BC081906, JAXUCZ010000005
      UniProtKB/TrEMBL
      A0A0H2UHT8
      Conserved Domains (2) summary
      PHA03253
      Location:96 → 212
      PHA03253; UL35; Provisional
      pfam14753
      Location:365 → 479
      DUF4475; Domain of unknown function (DUF4475)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      62706118..62715339 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063287397.1 → XP_063143467.1  protein FAM221B isoform X4

    2. XM_039109579.2 → XP_038965507.1  protein FAM221B isoform X3

      UniProtKB/TrEMBL
      A0A0H2UHT8
      Related
      ENSRNOP00000090764.2, ENSRNOT00000106988.2
      Conserved Domains (2) summary
      PTZ00449
      Location:13 → 242
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam14753
      Location:305 → 431
      FAM221; Protein FAM221A/B

    3. XM_008763669.4 → XP_008761891.1  protein FAM221B isoform X1

      UniProtKB/TrEMBL
      A0A0H2UHT8
      Related
      ENSRNOP00000031403.6, ENSRNOT00000029035.8
      Conserved Domains (2) summary
      PHA03253
      Location:96 → 212
      PHA03253; UL35; Provisional
      pfam14753
      Location:370 → 484
      DUF4475; Domain of unknown function (DUF4475)

    4. XM_017593272.3 → XP_017448761.1  protein FAM221B isoform X2

      UniProtKB/TrEMBL
      A0A0H2UHT8

    RNA

    1. XR_010066361.1 RNA Sequence

    2. XR_010066360.1 RNA Sequence

    3. XR_010066359.1 RNA Sequence

    4. XR_010066358.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q66HD8.1 GenPept UniProtKB/Swiss-Prot:Q66HD8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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