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    Mroh7 maestro heat-like repeat family member 7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298301, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Mroh7provided by RGD
    Official Full Name
    maestro heat-like repeat family member 7provided by RGD
    Primary source
    RGD:1563440
    See related
    EnsemblRapid:ENSRNOG00000058870 AllianceGenome:RGD:1563440
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Heatr8; RGD1563440
    Summary
    Predicted to be located in membrane. Predicted to be active in cytoplasm. Orthologous to human MROH7 (maestro heat like repeat family member 7). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Testes (RPKM 116.3), Heart (RPKM 12.3) and 3 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Mroh7 in Genome Data Viewer
    Location:
    5q34
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (126692649..126740180, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (121463826..121509233, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (126283868..126329157, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene prolyl-tRNA synthetase 2, mitochondrial Neighboring gene tetratricopeptide repeat domain 4 Neighboring gene family with sequence similarity 151, member A Neighboring gene acyl-CoA thioesterase 11 Neighboring gene uncharacterized LOC134479025

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach. Böhm D, et al. Oncol Rep, 2012 Aug. PMID 22664934, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC156808

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    maestro heat-like repeat-containing protein family member 7
    Names
    HEAT repeat containing 8
    HEAT repeat-containing protein 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001395081.1 → NP_001382010.1  maestro heat-like repeat-containing protein family member 7

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/Swiss-Prot
      A2RUW0
      Conserved Domains (1) summary
      pfam05109
      Location:15 → 302
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      126692649..126740180 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063287382.1 → XP_063143452.1  maestro heat-like repeat-containing protein family member 7 isoform X2

    2. XM_039109549.2 → XP_038965477.1  maestro heat-like repeat-containing protein family member 7 isoform X1

      UniProtKB/Swiss-Prot
      A2RUW0
      Conserved Domains (1) summary
      pfam05109
      Location:15 → 302
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

    3. XM_039109547.2 → XP_038965475.1  maestro heat-like repeat-containing protein family member 7 isoform X1

      UniProtKB/Swiss-Prot
      A2RUW0
      Conserved Domains (1) summary
      pfam05109
      Location:15 → 302
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

    4. XM_039109548.2 → XP_038965476.1  maestro heat-like repeat-containing protein family member 7 isoform X1

      UniProtKB/Swiss-Prot
      A2RUW0
      Conserved Domains (1) summary
      pfam05109
      Location:15 → 302
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

    5. XM_063287384.1 → XP_063143454.1  maestro heat-like repeat-containing protein family member 7 isoform X2

    6. XM_039109544.2 → XP_038965472.1  maestro heat-like repeat-containing protein family member 7 isoform X1

      UniProtKB/Swiss-Prot
      A2RUW0
      Conserved Domains (1) summary
      pfam05109
      Location:15 → 302
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

    7. XM_008763864.3 → XP_008762086.1  maestro heat-like repeat-containing protein family member 7 isoform X1

      See identical proteins and their annotated locations for XP_008762086.1

      UniProtKB/Swiss-Prot
      A2RUW0
      Related
      ENSRNOP00000072770.2, ENSRNOT00000089934.3
      Conserved Domains (1) summary
      pfam05109
      Location:15 → 302
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

    8. XM_063287383.1 → XP_063143453.1  maestro heat-like repeat-containing protein family member 7 isoform X2

    9. XM_039109551.2 → XP_038965479.1  maestro heat-like repeat-containing protein family member 7 isoform X2

      UniProtKB/Swiss-Prot
      A2RUW0
      Conserved Domains (1) summary
      pfam05109
      Location:15 → 302
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

    10. XM_039109545.1 → XP_038965473.1  maestro heat-like repeat-containing protein family member 7 isoform X1

      UniProtKB/Swiss-Prot
      A2RUW0
      Conserved Domains (1) summary
      pfam05109
      Location:15 → 302
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

    11. XM_017593266.3 → XP_017448755.1  maestro heat-like repeat-containing protein family member 7 isoform X1

      UniProtKB/Swiss-Prot
      A2RUW0
      Conserved Domains (1) summary
      pfam05109
      Location:15 → 302
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

    12. XM_063287385.1 → XP_063143455.1  maestro heat-like repeat-containing protein family member 7 isoform X3

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001100965.2: Suppressed sequence

      Description
      NM_001100965.2: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A2RUW0.1 GenPept UniProtKB/Swiss-Prot:A2RUW0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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