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    Mob1a MOB kinase activator 1A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 297387, updated on 2-Nov-2024

    Summary

    Official Symbol
    Mob1aprovided by RGD
    Official Full Name
    MOB kinase activator 1Aprovided by RGD
    Primary source
    RGD:1307014
    See related
    EnsemblRapid:ENSRNOG00000059474 AllianceGenome:RGD:1307014
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Mobk1b; Mobkl1b
    Summary
    Predicted to enable protein serine/threonine kinase activator activity. Predicted to be involved in hippo signaling. Predicted to be active in cytoplasm and nucleus. Orthologous to human MOB1A (MOB kinase activator 1A). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Thymus (RPKM 544.3), Spleen (RPKM 542.0) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Mob1a in Genome Data Viewer
    Location:
    4q34
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (117389278..117406255)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (115831581..115848561)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (115024927..115041904)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 4 member 5 Neighboring gene uncharacterized LOC134486596 Neighboring gene methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Neighboring gene uncharacterized LOC134486597 Neighboring gene bolA family member 3 Neighboring gene tet methylcytosine dioxygenase 3 Neighboring gene uncharacterized LOC102548361

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC124888

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein serine/threonine kinase activator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in hippo signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in hippo signaling ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    MOB kinase activator 1A
    Names
    Mob4B protein-like
    mob1 homolog 1B
    mps one binder kinase activator-like 1B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033891.1NP_001029063.1  MOB kinase activator 1A

      See identical proteins and their annotated locations for NP_001029063.1

      Status: PROVISIONAL

      Source sequence(s)
      BC101879
      UniProtKB/Swiss-Prot
      Q3T1J9
      UniProtKB/TrEMBL
      A0A8I5ZK61, A6IAL9
      Related
      ENSRNOP00000072053.2, ENSRNOT00000090987.3
      Conserved Domains (1) summary
      pfam03637
      Location:33204
      Mob1_phocein; Mob1/phocein family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      117389278..117406255
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)