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    Gadd45gip1 GADD45G interacting protein 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 288916, updated on 2-Nov-2024

    Summary

    Official Symbol
    Gadd45gip1provided by RGD
    Official Full Name
    GADD45G interacting protein 1provided by RGD
    Primary source
    RGD:1309249
    See related
    EnsemblRapid:ENSRNOG00000003011 AllianceGenome:RGD:1309249
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    MRP-L59
    Summary
    Predicted to enable mitochondrial ribosome binding activity. Predicted to act upstream of or within positive regulation of cell population proliferation and positive regulation of oxidative phosphorylation. Predicted to be located in nucleoplasm. Predicted to be part of ribonucleoprotein complex. Predicted to be active in mitochondrion. Orthologous to human GADD45GIP1 (GADD45G interacting protein 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Muscle (RPKM 515.6), Adrenal (RPKM 376.1) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Gadd45gip1 in Genome Data Viewer
    Location:
    19q11
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (40225503..40228052, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (23320662..23323211, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (25946979..25949528)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene phenylalanyl-tRNA synthetase subunit alpha Neighboring gene calreticulin Neighboring gene RAD23 homolog A, nucleotide excision repair protein Neighboring gene uncharacterized LOC134483324 Neighboring gene DAN domain BMP antagonist family member 5 Neighboring gene uncharacterized LOC134483325 Neighboring gene nuclear factor I X

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables mitochondrial ribosome binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    large ribosomal subunit protein mL64
    Names
    39S ribosomal protein L59, mitochondrial
    growth arrest and DNA damage-inducible proteins-interacting protein 1
    growth arrest and DNA-damage-inducible, gamma interacting protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100504.1NP_001093974.1  large ribosomal subunit protein mL64

      See identical proteins and their annotated locations for NP_001093974.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000019
      UniProtKB/Swiss-Prot
      Q5XJW2
      UniProtKB/TrEMBL
      A6IY72
      Related
      ENSRNOP00000004027.4, ENSRNOT00000004027.9
      Conserved Domains (1) summary
      pfam10147
      Location:1211
      CR6_interact; Growth arrest and DNA-damage-inducible proteins-interacting protein 1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      40225503..40228052 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)