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    GLRA1 glycine receptor alpha 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 281783, updated on 4-Oct-2024

    Summary

    Official Symbol
    GLRA1provided by VGNC
    Official Full Name
    glycine receptor alpha 1provided by VGNC
    Primary source
    VGNC:VGNC:29412
    See related
    BGD:BT12218; Ensembl:ENSBTAG00000014395
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    NEW
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    Genomic context

    See GLRA1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (63021619..63108191, complement)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112447461 Neighboring gene antioxidant 1 copper chaperone Neighboring gene G3BP stress granule assembly factor 1 Neighboring gene uncharacterized LOC132345775 Neighboring gene neuromedin U receptor 2 Neighboring gene small ribosomal subunit protein uS3-like

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables extracellularly glycine-gated chloride channel activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables glycine binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables transmembrane signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables transmitter-gated monoatomic ion channel activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in chloride transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in nervous system process IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in regulation of membrane potential IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    glycine receptor subunit alpha-1
    Names
    glycine receptor 48 kDa subunit
    glycine receptor alpha 1 subunit
    glycine receptor strychnine-binding subunit
    glycine receptor, alpha 1 (startle disease/hyperekplexia)
    glycine receptor, alpha 1 (startle disease/hyperekplexia, stiff man syndrome)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174321.2NP_776746.1  glycine receptor subunit alpha-1 precursor

      See identical proteins and their annotated locations for NP_776746.1

      Status: PROVISIONAL

      Source sequence(s)
      AF268375
      UniProtKB/Swiss-Prot
      P57695, Q9GKE9, Q9GKF0
      Related
      ENSBTAP00000019143.3, ENSBTAT00000019143.4
      Conserved Domains (1) summary
      TIGR00860
      Location:7446
      LIC; Cation transporter family protein

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      63021619..63108191 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)