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    RGS9 regulator of G protein signaling 9 [ Bos taurus (domestic cattle) ]

    Gene ID: 281453, updated on 10-Oct-2024

    Summary

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    Official Symbol
    RGS9provided by VGNC
    Official Full Name
    regulator of G protein signaling 9provided by VGNC
    Primary source
    VGNC:VGNC:33926
    See related
    Ensembl:ENSBTAG00000017751
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See RGS9 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (61983611..62043250)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene archaelysin family metallopeptidase 2 Neighboring gene G protein subunit alpha 13 Neighboring gene uncharacterized LOC101907107 Neighboring gene uncharacterized LOC112442742 Neighboring gene uncharacterized LOC112442583 Neighboring gene axin 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural information and membrane binding of truncated RGS9-1 Anchor Protein and its C-terminal hydrophobic segment. Bernier SC, et al. Biochim Biophys Acta Biomembr, 2021 Apr 1. PMID 33453187
    2. The GTPase activating factor for transducin in rod photoreceptors is the complex between RGS9 and type 5 G protein beta subunit. Makino ER, et al. Proc Natl Acad Sci U S A, 1999 Mar 2. PMID 10051575, Free PMC Article
    3. Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A. Slep KC, et al. Nature, 2001 Feb 22. PMID 11234020
    4. RGS9, a GTPase accelerator for phototransduction. He W, et al. Neuron, 1998 Jan. PMID 9459445
    5. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Structural information and membrane binding of truncated RGS9-1 Anchor Protein and its C-terminal hydrophobic segment.
      Title: Structural information and membrane binding of truncated RGS9-1 Anchor Protein and its C-terminal hydrophobic segment.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC159844

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    regulator of G-protein signaling 9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174170.2 → NP_776595.1  regulator of G-protein signaling 9

      See identical proteins and their annotated locations for NP_776595.1

      Status: PROVISIONAL

      Source sequence(s)
      AF011357
      UniProtKB/Swiss-Prot
      O46469
      Conserved Domains (4) summary
      smart00224
      Location:222 → 280
      GGL; G protein gamma subunit-like motifs
      cd08739
      Location:292 → 412
      RGS_RGS9; Regulator of G protein signaling (RGS) domain found in the RGS9 protein
      cd04450
      Location:22 → 109
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
      pfam18148
      Location:106 → 205
      RGS_DHEX; Regulator of G-protein signalling DHEX domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      61983611..62043250
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024979596.2 → XP_024835364.1  regulator of G-protein signaling 9 isoform X4

      UniProtKB/TrEMBL
      A0AAA9TQY0
      Related
      ENSBTAP00000099733.1, ENSBTAT00000095863.1
      Conserved Domains (3) summary
      smart00224
      Location:196 → 254
      GGL; G protein gamma subunit-like motifs
      cd08739
      Location:266 → 386
      RGS_RGS9; Regulator of G protein signaling (RGS) domain found in the RGS9 protein
      cd04450
      Location:1 → 83
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...

    2. XM_024979594.2 → XP_024835362.1  regulator of G-protein signaling 9 isoform X2

      UniProtKB/TrEMBL
      F1MYX4
      Conserved Domains (3) summary
      smart00224
      Location:222 → 280
      GGL; G protein gamma subunit-like motifs
      cd08739
      Location:292 → 412
      RGS_RGS9; Regulator of G protein signaling (RGS) domain found in the RGS9 protein
      cd04450
      Location:22 → 109
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...

    3. XM_059877711.1 → XP_059733694.1  regulator of G-protein signaling 9 isoform X5

    4. XM_024979595.2 → XP_024835363.1  regulator of G-protein signaling 9 isoform X3

      UniProtKB/TrEMBL
      F1MYX4
      Conserved Domains (3) summary
      smart00224
      Location:222 → 280
      GGL; G protein gamma subunit-like motifs
      cd08739
      Location:292 → 412
      RGS_RGS9; Regulator of G protein signaling (RGS) domain found in the RGS9 protein
      cd04450
      Location:22 → 109
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...

    5. XM_024979593.2 → XP_024835361.1  regulator of G-protein signaling 9 isoform X1

      UniProtKB/TrEMBL
      F1MYX4
      Related
      ENSBTAP00000023605.7, ENSBTAT00000023605.7
      Conserved Domains (3) summary
      smart00224
      Location:222 → 280
      GGL; G protein gamma subunit-like motifs
      cd08739
      Location:292 → 412
      RGS_RGS9; Regulator of G protein signaling (RGS) domain found in the RGS9 protein
      cd04450
      Location:22 → 109
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...

    6. XM_024979597.2 → XP_024835365.1  regulator of G-protein signaling 9 isoform X6

      UniProtKB/TrEMBL
      F1MYX4
      Conserved Domains (3) summary
      smart00224
      Location:169 → 227
      GGL; G protein gamma subunit-like motifs
      cd08739
      Location:239 → 359
      RGS_RGS9; Regulator of G protein signaling (RGS) domain found in the RGS9 protein
      cd04450
      Location:22 → 109
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...

    7. XM_059877712.1 → XP_059733695.1  regulator of G-protein signaling 9 isoform X7

    RNA

    1. XR_003030579.2 RNA Sequence

    2. XR_003030580.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O46469.1 GenPept UniProtKB/Swiss-Prot:O46469

    Gene LinkOut

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