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    Trp53i11 transformation related protein 53 inducible protein 11 [ Mus musculus (house mouse) ]

    Gene ID: 277414, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Trp53i11provided by MGI
    Official Full Name
    transformation related protein 53 inducible protein 11provided by MGI
    Primary source
    MGI:MGI:2670995
    See related
    Ensembl:ENSMUSG00000068735 AllianceGenome:MGI:2670995
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tp53i11
    Summary
    Predicted to be located in membrane. Is expressed in nervous system and neural retina. Orthologous to human TP53I11 (tumor protein p53 inducible protein 11). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in thymus adult (RPKM 53.1), colon adult (RPKM 33.8) and 24 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Trp53i11 in Genome Data Viewer
    Location:
    2 E1; 2 51.37 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (93017694..93032102)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (93187349..93201757)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700055L01 gene Neighboring gene predicted gene, 32627 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:93032831-93033064 Neighboring gene predicted gene, 32683 Neighboring gene tetraspanin 18 Neighboring gene predicted gene, 32824 Neighboring gene predicted gene, 39882

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells. Sabbagh MF, et al. Elife, 2018 Sep 6. PMID 30188322, Free PMC Article
    2. A dual-strategy expression screen for candidate connectivity labels in the developing thalamus. Bibollet-Bahena O, et al. PLoS One, 2017. PMID 28558017, Free PMC Article
    3. Genomic analysis of mouse retinal development. Blackshaw S, et al. PLoS Biol, 2004 Sep. PMID 15226823, Free PMC Article
    4. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
    5. A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Thompson CL, et al. Neuron, 2014 Jul 16. PMID 24952961, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tumor protein p53-inducible protein 11
    Names
    Trp53 inducible protein 11 (Trp53i11)
    p53-induced gene 11 protein

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025246.3 → NP_001020417.1  tumor protein p53-inducible protein 11 isoform b

      See identical proteins and their annotated locations for NP_001020417.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks an alternate exon in the 5' UTR and uses an alternate splice junction compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 3 and 4 both encode the same isoform (b).
      Source sequence(s)
      AL683882, AL691472
      Consensus CDS
      CCDS16452.1
      UniProtKB/Swiss-Prot
      Q3UQL4, Q4QQM4
      Related
      ENSMUSP00000088042.5, ENSMUST00000090554.11
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    2. NM_001356535.2 → NP_001343464.1  tumor protein p53-inducible protein 11 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 both encode the same isoform (a).
      Source sequence(s)
      AL683882, AL691472
      Conserved Domains (1) summary
      pfam14936
      Location:25 → 203
      p53-inducible11; tumor protein p53-inducible protein 11

    3. NM_001356536.2 → NP_001343465.1  tumor protein p53-inducible protein 11 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a).
      Source sequence(s)
      AL683882, AL691472
      Conserved Domains (1) summary
      pfam14936
      Location:25 → 203
      p53-inducible11; tumor protein p53-inducible protein 11

    4. NM_001356537.2 → NP_001343466.1  tumor protein p53-inducible protein 11 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate splice junction compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 3 and 4 both encode the same isoform (b).
      Source sequence(s)
      AL683882, AL691472
      Consensus CDS
      CCDS16452.1
      UniProtKB/Swiss-Prot
      Q3UQL4, Q4QQM4
      Related
      ENSMUST00000127173.2
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    RNA

    1. NR_151503.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 3' end compared to variant 1. This variant is represented as non-coding because it lacks the entire coding region found in variant 1.
      Source sequence(s)
      AL683882
      Related
      ENSMUST00000132182.2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      93017694..93032102
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036162275.1 → XP_036018168.1  tumor protein p53-inducible protein 11 isoform X1

      Conserved Domains (1) summary
      pfam14936
      Location:25 → 203
      p53-inducible11; tumor protein p53-inducible protein 11

    2. XM_030251698.2 → XP_030107558.1  tumor protein p53-inducible protein 11 isoform X2

      UniProtKB/Swiss-Prot
      Q3UQL4, Q4QQM4
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    3. XM_036162277.1 → XP_036018170.1  tumor protein p53-inducible protein 11 isoform X1

      Conserved Domains (1) summary
      pfam14936
      Location:25 → 203
      p53-inducible11; tumor protein p53-inducible protein 11

    4. XM_030251700.2 → XP_030107560.1  tumor protein p53-inducible protein 11 isoform X2

      UniProtKB/Swiss-Prot
      Q3UQL4, Q4QQM4
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    5. XM_030251697.2 → XP_030107557.1  tumor protein p53-inducible protein 11 isoform X1

      Conserved Domains (1) summary
      pfam14936
      Location:25 → 203
      p53-inducible11; tumor protein p53-inducible protein 11

    6. XM_036162280.1 → XP_036018173.1  tumor protein p53-inducible protein 11 isoform X2

      UniProtKB/Swiss-Prot
      Q3UQL4, Q4QQM4
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    7. XM_030251699.2 → XP_030107559.1  tumor protein p53-inducible protein 11 isoform X2

      UniProtKB/Swiss-Prot
      Q3UQL4, Q4QQM4
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    8. XM_006499685.4 → XP_006499748.1  tumor protein p53-inducible protein 11 isoform X2

      See identical proteins and their annotated locations for XP_006499748.1

      UniProtKB/Swiss-Prot
      Q3UQL4, Q4QQM4
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    9. XM_017318948.2 → XP_017174437.1  tumor protein p53-inducible protein 11 isoform X1

      Conserved Domains (1) summary
      pfam14936
      Location:25 → 203
      p53-inducible11; tumor protein p53-inducible protein 11

    10. XM_036162281.1 → XP_036018174.1  tumor protein p53-inducible protein 11 isoform X2

      UniProtKB/Swiss-Prot
      Q3UQL4, Q4QQM4
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    11. XM_036162276.1 → XP_036018169.1  tumor protein p53-inducible protein 11 isoform X1

      Conserved Domains (1) summary
      pfam14936
      Location:25 → 203
      p53-inducible11; tumor protein p53-inducible protein 11

    12. XM_036162279.1 → XP_036018172.1  tumor protein p53-inducible protein 11 isoform X2

      UniProtKB/Swiss-Prot
      Q3UQL4, Q4QQM4
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    13. XM_036162278.1 → XP_036018171.1  tumor protein p53-inducible protein 11 isoform X2

      UniProtKB/Swiss-Prot
      Q3UQL4, Q4QQM4
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    14. XM_006499681.3 → XP_006499744.1  tumor protein p53-inducible protein 11 isoform X2

      See identical proteins and their annotated locations for XP_006499744.1

      UniProtKB/Swiss-Prot
      Q3UQL4, Q4QQM4
      Related
      ENSMUSP00000106897.2, ENSMUST00000111266.8
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4QQM4.1 GenPept UniProtKB/Swiss-Prot:Q4QQM4

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