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    Ccdc153 coiled-coil domain containing 153 [ Mus musculus (house mouse) ]

    Gene ID: 270150, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Ccdc153provided by MGI
    Official Full Name
    coiled-coil domain containing 153provided by MGI
    Primary source
    MGI:MGI:2448587
    See related
    Ensembl:ENSMUSG00000070306 AllianceGenome:MGI:2448587
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Drc12
    Summary
    Predicted to enable identical protein binding activity. Predicted to be located in cytoplasm; cytoskeleton; and motile cilium. Orthologous to human DRC12 (dynein regulatory complex subunit 12 homolog). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in lung adult (RPKM 4.7), ovary adult (RPKM 3.9) and 5 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ccdc153 in Genome Data Viewer
    Location:
    9 A5.2; 9 24.84 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (44151961..44158240)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (44240677..44247306)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_23959 Neighboring gene melanoma cell adhesion molecule Neighboring gene Casitas B-lineage lymphoma Neighboring gene STARR-positive B cell enhancer ABC_E5062 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:44046702-44046855 Neighboring gene NHERF family PDZ scaffold protein 4 Neighboring gene NLR family member X1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Stauber M, et al. Dev Biol, 2017 Mar 15. PMID 27914912
    2. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
    3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, et al. Nature, 2002 Dec 5. PMID 12466851
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in motile cilium IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    dynein regulatory complex protein 12; coiled-coil domain-containing protein 153

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081369.3 → NP_001074838.2  dynein regulatory complex protein 12 isoform 1

      See identical proteins and their annotated locations for NP_001074838.2

      Status: VALIDATED

      Source sequence(s)
      AC124577
      Consensus CDS
      CCDS52778.1
      UniProtKB/Swiss-Prot
      P0C7Q1
      UniProtKB/TrEMBL
      A0A1L1STT2
      Related
      ENSMUSP00000090082.4, ENSMUST00000092426.5
      Conserved Domains (1) summary
      cl19219
      Location:24 → 124
      DUF342; Protein of unknown function (DUF342)

    2. NM_001360344.2 → NP_001347273.1  dynein regulatory complex protein 12 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC124577
      Consensus CDS
      CCDS90547.1
      UniProtKB/TrEMBL
      A0A1L1SRN4, A0A1L1STT2
      Related
      ENSMUSP00000149540.2, ENSMUST00000213891.2
      Conserved Domains (1) summary
      PRK00409
      Location:44 → 154
      PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed

    3. NM_001410639.1 → NP_001397568.1  dynein regulatory complex protein 12 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC124577
      UniProtKB/TrEMBL
      A0A1L1SRN4

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      44151961..44158240
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036155028.1 → XP_036010921.1  coiled-coil domain-containing protein 153 isoform X2

      UniProtKB/TrEMBL
      A0A1L1STT2
      Related
      ENSMUSP00000150478.2, ENSMUST00000216632.2
      Conserved Domains (1) summary
      PRK00409
      Location:51 → 151
      PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0C7Q1.1 GenPept UniProtKB/Swiss-Prot:P0C7Q1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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