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    knk1 AAA family ATPase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541249, updated on 18-Sep-2024

    Summary

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    Official Symbol
    knk1
    Official Full Name
    AAA family ATPase
    Primary source
    PomBase:SPBC947.01
    Locus tag
    SPOM_SPBC947.01
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    alf1
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    Genomic context

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    See knk1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003423.3 (679903..682666, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene putative NatC N-acetyltransferase non-catalytic subunit Naa38 Neighboring gene AP-1 adaptor complex beta subunit Apl2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene decaprenyl diphosphate synthase subunit Dps1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Oscillatory AAA+ ATPase Knk1 constitutes a novel morphogenetic pathway in fission yeast. Scheffler K, et al. Proc Natl Acad Sci U S A, 2014 Dec 16. PMID 25422470, Free PMC Article
    2. Chromatin remodeller Fun30(Fft3) induces nucleosome disassembly to facilitate RNA polymerase II elongation. Lee J, et al. Nat Commun, 2017 Feb 20. PMID 28218250, Free PMC Article
    3. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article
    4. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables ATP hydrolysis activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables microtubule severing ATPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in microtubule bundle formation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in microtubule severing ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell division site HDA PubMed 
    is_active_in cell tip HDA PubMed 
    is_active_in medial cortex septin ring IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in new growing cell tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in old growing cell tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    AAA family ATPase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      679903..682666 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021182.3 → NP_595275.1  AAA family ATPase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595275.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O43078
      Conserved Domains (4) summary
      smart00382
      Location:413 → 556
      AAA; ATPases associated with a variety of cellular activities
      pfam00004
      Location:415 → 554
      AAA; ATPase family associated with various cellular activities (AAA)
      pfam09336
      Location:623 → 657
      Vps4_C; Vps4 C terminal oligomerization domain
      cl21455
      Location:382 → 432
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein
    Heading Accession and Version

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