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    Defb13 defensin beta 13 [ Mus musculus (house mouse) ]

    Gene ID: 246083, updated on 2-Nov-2024

    Summary

    Official Symbol
    Defb13provided by MGI
    Official Full Name
    defensin beta 13provided by MGI
    Primary source
    MGI:MGI:2179203
    See related
    Ensembl:ENSMUSG00000044222 AllianceGenome:MGI:2179203
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BD-13
    Summary
    Predicted to enable lipid binding activity. Predicted to be involved in defense response to bacterium. Predicted to be located in extracellular region. Orthologous to human DEFB107A (defensin beta 107A) and DEFB107B (defensin beta 107B). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward genital fat pad adult (RPKM 2.0) See more
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    Genomic context

    See Defb13 in Genome Data Viewer
    Location:
    8 A2; 8 10.68 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (22436771..22438866)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (21946755..21948622)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 36879 Neighboring gene defensin beta 15 Neighboring gene defensin beta 35 Neighboring gene predicted gene, 29821 Neighboring gene STARR-seq mESC enhancer starr_20895 Neighboring gene family with sequence similarity 90, member A1A Neighboring gene coiled-coil domain containing 70

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables lipid binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in defense response to bacterium IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_139223.5NP_631969.1  beta-defensin 13 precursor

      See identical proteins and their annotated locations for NP_631969.1

      Status: VALIDATED

      Source sequence(s)
      AL590619
      Consensus CDS
      CCDS40290.1
      UniProtKB/Swiss-Prot
      A2A4E3, Q8R2I4
      Related
      ENSMUSP00000060997.4, ENSMUST00000060587.4
      Conserved Domains (1) summary
      pfam13841
      Location:3058
      Defensin_beta_2; Beta defensin

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      22436771..22438866
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)