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    Phf20l1 PHD finger protein 20-like 1 [ Mus musculus (house mouse) ]

    Gene ID: 239510, updated on 18-Sep-2024

    Summary

    Official Symbol
    Phf20l1provided by MGI
    Official Full Name
    PHD finger protein 20-like 1provided by MGI
    Primary source
    MGI:MGI:2444412
    See related
    Ensembl:ENSMUSG00000072501 AllianceGenome:MGI:2444412
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CGI-72; E130113K22Rik
    Summary
    Predicted to enable metal ion binding activity. Predicted to be involved in histone acetylation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of NSL complex. Is expressed in early conceptus; inner cell mass; and oocyte. Orthologous to human PHF20L1 (PHD finger protein 20 like 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in CNS E18 (RPKM 6.6), CNS E14 (RPKM 6.2) and 25 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Phf20l1 in Genome Data Viewer
    Location:
    15 D1- D2; 15 29.3 cM
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (66449354..66519821)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (66577500..66647043)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene dynein axonemal assembly factor 11 Neighboring gene STARR-seq mESC enhancer starr_38888 Neighboring gene predicted gene, 31006 Neighboring gene STARR-positive B cell enhancer mm9_chr15:66392494-66392795 Neighboring gene transmembrane protein 71 Neighboring gene STARR-positive B cell enhancer mm9_chr15:66511565-66511866 Neighboring gene thyroglobulin Neighboring gene STARR-positive B cell enhancer mm9_chr15:66616909-66617209 Neighboring gene STARR-positive B cell enhancer ABC_E5484 Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:66650248-66650357 Neighboring gene VISTA enhancer mm104 Neighboring gene src-like adaptor Neighboring gene STARR-positive B cell enhancer ABC_E5485 Neighboring gene predicted gene, 46514

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables methylation-dependent protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables methylation-dependent protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    part_of NSL complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    PHD finger protein 20-like protein 1
    Names
    tudor domain-containing protein PHF20L1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081409.2NP_001074878.1  PHD finger protein 20-like protein 1 isoform 3

      See identical proteins and their annotated locations for NP_001074878.1

      Status: VALIDATED

      Source sequence(s)
      AC163443
      Consensus CDS
      CCDS49621.1
      UniProtKB/Swiss-Prot
      A6H5Y9, Q80UN6, Q8BPP8, Q8BQQ6, Q8BS11, Q8C8H9, Q8CCJ9
      Related
      ENSMUSP00000155487.2, ENSMUST00000229160.2
      Conserved Domains (5) summary
      cd04508
      Location:90135
      TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
      PTZ00449
      Location:315506
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd15633
      Location:683728
      PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
      pfam16660
      Location:318383
      PHD20L1_u1; PHD finger protein 20-like protein 1
      cl17705
      Location:368
      MBT; mbt repeat
    2. NM_001418886.1NP_001405815.1  PHD finger protein 20-like protein 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC163443
    3. NM_001418887.1NP_001405816.1  PHD finger protein 20-like protein 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC163443
    4. NM_001418888.1NP_001405817.1  PHD finger protein 20-like protein 1 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC163443
    5. NM_001418889.1NP_001405818.1  PHD finger protein 20-like protein 1 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC163443
      UniProtKB/TrEMBL
      A0A2R8VHV1
    6. NM_001418890.1NP_001405819.1  PHD finger protein 20-like protein 1 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC163443
      UniProtKB/TrEMBL
      A0A2R8VHV1
      Related
      ENSMUSP00000155465.2, ENSMUST00000230948.2
    7. NM_001418891.1NP_001405820.1  PHD finger protein 20-like protein 1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC163443
    8. NM_001418892.1NP_001405821.1  PHD finger protein 20-like protein 1 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC163443
    9. NM_001418893.1NP_001405822.1  PHD finger protein 20-like protein 1 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC163443
    10. NM_001418894.1NP_001405823.1  PHD finger protein 20-like protein 1 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC163443
    11. NM_001418896.1NP_001405825.1  PHD finger protein 20-like protein 1 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC163443
    12. NM_001418897.1NP_001405826.1  PHD finger protein 20-like protein 1 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC163443
    13. NM_001418898.1NP_001405827.1  PHD finger protein 20-like protein 1 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AC163443
    14. NM_001418899.1NP_001405828.1  PHD finger protein 20-like protein 1 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AC163443
    15. NM_001418900.1NP_001405829.1  PHD finger protein 20-like protein 1 isoform 11

      Status: VALIDATED

      Source sequence(s)
      AC163443
    16. NM_001418901.1NP_001405830.1  PHD finger protein 20-like protein 1 isoform 11

      Status: VALIDATED

      Source sequence(s)
      AC163443
      Related
      ENSMUSP00000155575.2, ENSMUST00000230882.2
    17. NM_001418902.1NP_001405831.1  PHD finger protein 20-like protein 1 isoform 12

      Status: VALIDATED

      Source sequence(s)
      AC163443
    18. NM_001418903.1NP_001405832.1  PHD finger protein 20-like protein 1 isoform 12

      Status: VALIDATED

      Source sequence(s)
      AC163443
    19. NM_001418904.1NP_001405833.1  PHD finger protein 20-like protein 1 isoform 13

      Status: VALIDATED

      Source sequence(s)
      AC163443
    20. NM_001418905.1NP_001405834.1  PHD finger protein 20-like protein 1 isoform 13

      Status: VALIDATED

      Source sequence(s)
      AC163443

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      66449354..66519821
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006520918.4XP_006520981.1  PHD finger protein 20-like protein 1 isoform X2

      Conserved Domains (5) summary
      cd04508
      Location:90135
      TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
      PTZ00449
      Location:319510
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd15633
      Location:687732
      PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
      pfam16660
      Location:322387
      PHD20L1_u1; PHD finger protein 20-like protein 1
      cl17705
      Location:368
      MBT; mbt repeat
    2. XM_030248546.2XP_030104406.1  PHD finger protein 20-like protein 1 isoform X5

      Conserved Domains (5) summary
      cd04508
      Location:90135
      TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
      PTZ00449
      Location:290481
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd15633
      Location:658703
      PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
      pfam16660
      Location:293358
      PHD20L1_u1; PHD finger protein 20-like protein 1
      cl17705
      Location:368
      MBT; mbt repeat
    3. XM_030248545.2XP_030104405.1  PHD finger protein 20-like protein 1 isoform X4

      UniProtKB/Swiss-Prot
      A6H5Y9, Q80UN6, Q8BPP8, Q8BQQ6, Q8BS11, Q8C8H9, Q8CCJ9
      Conserved Domains (5) summary
      cd04508
      Location:90135
      TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
      PTZ00449
      Location:315506
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd15633
      Location:683728
      PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
      pfam16660
      Location:318383
      PHD20L1_u1; PHD finger protein 20-like protein 1
      cl17705
      Location:368
      MBT; mbt repeat
    4. XM_006520919.5XP_006520982.1  PHD finger protein 20-like protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A5S8DHC4
      Related
      ENSMUSP00000035682.10, ENSMUST00000048188.10
      Conserved Domains (5) summary
      cd04508
      Location:90135
      TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
      PTZ00449
      Location:316507
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd15633
      Location:684729
      PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
      pfam16660
      Location:319384
      PHD20L1_u1; PHD finger protein 20-like protein 1
      cl17705
      Location:368
      MBT; mbt repeat
    5. XM_030248548.2XP_030104408.1  PHD finger protein 20-like protein 1 isoform X7

      Conserved Domains (1) summary
      cd15633
      Location:262307
      PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
    6. XM_006520917.5XP_006520980.1  PHD finger protein 20-like protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006520980.1

      Conserved Domains (5) summary
      cd04508
      Location:90135
      TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
      PTZ00449
      Location:320511
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd15633
      Location:688733
      PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
      pfam16660
      Location:323388
      PHD20L1_u1; PHD finger protein 20-like protein 1
      cl17705
      Location:368
      MBT; mbt repeat
    7. XM_030248544.2XP_030104404.1  PHD finger protein 20-like protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A5S8DHC4
      Conserved Domains (5) summary
      cd04508
      Location:90135
      TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
      PTZ00449
      Location:316507
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd15633
      Location:684729
      PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
      pfam16660
      Location:319384
      PHD20L1_u1; PHD finger protein 20-like protein 1
      cl17705
      Location:368
      MBT; mbt repeat
    8. XM_036159397.1XP_036015290.1  PHD finger protein 20-like protein 1 isoform X7

      Conserved Domains (1) summary
      cd15633
      Location:262307
      PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
    9. XM_036159396.1XP_036015289.1  PHD finger protein 20-like protein 1 isoform X7

      Conserved Domains (1) summary
      cd15633
      Location:262307
      PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
    10. XM_030248547.2XP_030104407.1  PHD finger protein 20-like protein 1 isoform X7

      Conserved Domains (1) summary
      cd15633
      Location:262307
      PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
    11. XM_030248549.1XP_030104409.1  PHD finger protein 20-like protein 1 isoform X7

      Conserved Domains (1) summary
      cd15633
      Location:262307
      PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)

    RNA

    1. XR_003951380.1 RNA Sequence

    2. XR_003951377.1 RNA Sequence

    3. XR_003951385.2 RNA Sequence

    4. XR_003951382.2 RNA Sequence

    5. XR_003951379.2 RNA Sequence

    6. XR_004938835.1 RNA Sequence

    7. XR_003951381.1 RNA Sequence

    8. XR_001781530.3 RNA Sequence

    9. XR_001781529.3 RNA Sequence

    10. XR_003951375.2 RNA Sequence

    11. XR_001781531.3 RNA Sequence

    12. XR_001781528.3 RNA Sequence

    13. XR_001781525.3 RNA Sequence

    14. XR_001781524.3 RNA Sequence

    15. XR_001781526.3 RNA Sequence

    16. XR_003951378.2 RNA Sequence

    17. XR_003951376.2 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_178718.2: Suppressed sequence

      Description
      NM_178718.2: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.