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    Krt39 keratin 39 [ Mus musculus (house mouse) ]

    Gene ID: 237934, updated on 28-Oct-2024

    Summary

    Official Symbol
    Krt39provided by MGI
    Official Full Name
    keratin 39provided by MGI
    Primary source
    MGI:MGI:3588208
    See related
    Ensembl:ENSMUSG00000064165 AllianceGenome:MGI:3588208
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ka35; 4732494G06Rik
    Summary
    Predicted to enable structural molecule activity. Predicted to be involved in epithelial cell differentiation and intermediate filament organization. Predicted to be located in intermediate filament. Predicted to be active in cytoskeleton. Orthologous to human KRT39 (keratin 39). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
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    Genomic context

    See Krt39 in Genome Data Viewer
    Location:
    11 D; 11 62.92 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (99403786..99412164, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (99512960..99521338, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene keratin 20 Neighboring gene keratin 23 Neighboring gene STARR-seq mESC enhancer starr_30705 Neighboring gene keratin 40 Neighboring gene keratin associated protein 3-3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in epithelial cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intermediate filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in intermediate filament IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    keratin, type I cytoskeletal 39
    Names
    CK-39
    K39
    cytokeratin-39
    ortholog of type I hair keratin KA35
    type I hair keratin KA35

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213730.3NP_998895.2  keratin, type I cytoskeletal 39

      See identical proteins and their annotated locations for NP_998895.2

      Status: VALIDATED

      Source sequence(s)
      AL591417
      Consensus CDS
      CCDS25383.1
      UniProtKB/Swiss-Prot
      A2VCT4, Q0VDS4, Q6IFX4
      Related
      ENSMUSP00000076216.2, ENSMUST00000076948.2
      Conserved Domains (1) summary
      pfam00038
      Location:91401
      Filament; Intermediate filament protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      99403786..99412164 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)