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    Ccdc106 coiled-coil domain containing 106 [ Mus musculus (house mouse) ]

    Gene ID: 232821, updated on 28-Oct-2024

    Summary

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    Official Symbol
    Ccdc106provided by MGI
    Official Full Name
    coiled-coil domain containing 106provided by MGI
    Primary source
    MGI:MGI:2385900
    See related
    Ensembl:ENSMUSG00000035228 AllianceGenome:MGI:2385900
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be located in cytosol. Predicted to be active in nucleoplasm. Orthologous to human CCDC106 (coiled-coil domain containing 106). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Biased expression in CNS E18 (RPKM 12.7), frontal lobe adult (RPKM 10.3) and 14 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ccdc106 in Genome Data Viewer
    Location:
    7 A1; 7 2.92 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (5056870..5063784)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (5053842..5060785)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E3696 Neighboring gene zinc finger protein 784 Neighboring gene zinc finger protein 580 Neighboring gene STARR-positive B cell enhancer ABC_E4890 Neighboring gene predicted gene 15510 Neighboring gene STARR-positive B cell enhancer ABC_E3697 Neighboring gene STARR-positive B cell enhancer ABC_E9020 Neighboring gene STARR-positive B cell enhancer ABC_E4891 Neighboring gene U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 Neighboring gene epsin 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex. Pereira JD, et al. Proc Natl Acad Sci U S A, 2010 Sep 7. PMID 20798045, Free PMC Article
    2. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article
    3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    General gene information

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    Homology

    Clone Names

    • MGC27915

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 106

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001290429.2 → NP_001277358.1  coiled-coil domain-containing protein 106 isoform a

      See identical proteins and their annotated locations for NP_001277358.1

      Status: VALIDATED

      Source sequence(s)
      AC162893
      Consensus CDS
      CCDS80660.1
      UniProtKB/TrEMBL
      E9QPN6
      Conserved Domains (1) summary
      pfam15794
      Location:117 → 336
      CCDC106; Coiled-coil domain-containing protein 106

    2. NM_001290432.2 → NP_001277361.1  coiled-coil domain-containing protein 106 isoform b

      See identical proteins and their annotated locations for NP_001277361.1

      Status: VALIDATED

      Source sequence(s)
      AC162893
      Consensus CDS
      CCDS20757.1
      UniProtKB/Swiss-Prot
      Q3ULM0, Q8K5E2, Q8VEI0
      Conserved Domains (1) summary
      pfam15794
      Location:57 → 273
      CCDC106; Coiled-coil domain-containing protein 106

    3. NM_001420706.1 → NP_001407635.1  coiled-coil domain-containing protein 106 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC162893
      UniProtKB/TrEMBL
      E9QPN6

    4. NM_001420707.1 → NP_001407636.1  coiled-coil domain-containing protein 106 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC162893
      UniProtKB/TrEMBL
      E9QPN6
      Related
      ENSMUSP00000104211.2, ENSMUST00000108571.9

    5. NM_001420708.1 → NP_001407637.1  coiled-coil domain-containing protein 106 isoform c

      Status: VALIDATED

      Source sequence(s)
      AC162893

    6. NM_001420709.1 → NP_001407638.1  coiled-coil domain-containing protein 106 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC162893
      UniProtKB/Swiss-Prot
      Q3ULM0, Q8K5E2, Q8VEI0

    7. NM_001420710.1 → NP_001407639.1  coiled-coil domain-containing protein 106 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC162893
      UniProtKB/Swiss-Prot
      Q3ULM0, Q8K5E2, Q8VEI0

    8. NM_001420711.1 → NP_001407640.1  coiled-coil domain-containing protein 106 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC162893
      UniProtKB/Swiss-Prot
      Q3ULM0, Q8K5E2, Q8VEI0

    9. NM_001420712.1 → NP_001407641.1  coiled-coil domain-containing protein 106 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC162893
      UniProtKB/Swiss-Prot
      Q3ULM0, Q8K5E2, Q8VEI0

    10. NM_001420713.1 → NP_001407642.1  coiled-coil domain-containing protein 106 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC162893
      UniProtKB/Swiss-Prot
      Q3ULM0, Q8K5E2, Q8VEI0

    11. NM_001420714.1 → NP_001407643.1  coiled-coil domain-containing protein 106 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC162893
      UniProtKB/Swiss-Prot
      Q3ULM0, Q8K5E2, Q8VEI0

    12. NM_001420715.1 → NP_001407644.1  coiled-coil domain-containing protein 106 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC162893
      UniProtKB/Swiss-Prot
      Q3ULM0, Q8K5E2, Q8VEI0

    13. NM_001420716.1 → NP_001407645.1  coiled-coil domain-containing protein 106 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC162893
      UniProtKB/Swiss-Prot
      Q3ULM0, Q8K5E2, Q8VEI0

    14. NM_001420717.1 → NP_001407646.1  coiled-coil domain-containing protein 106 isoform d

      Status: VALIDATED

      Source sequence(s)
      AC162893

    15. NM_001420718.1 → NP_001407647.1  coiled-coil domain-containing protein 106 isoform e

      Status: VALIDATED

      Source sequence(s)
      AC162893
      Related
      ENSMUSP00000146775.2, ENSMUST00000207974.2

    16. NM_146178.3 → NP_666290.2  coiled-coil domain-containing protein 106 isoform b

      See identical proteins and their annotated locations for NP_666290.2

      Status: VALIDATED

      Source sequence(s)
      AC162893
      Consensus CDS
      CCDS20757.1
      UniProtKB/Swiss-Prot
      Q3ULM0, Q8K5E2, Q8VEI0
      Related
      ENSMUSP00000041033.6, ENSMUST00000045543.8
      Conserved Domains (1) summary
      pfam15794
      Location:57 → 273
      CCDC106; Coiled-coil domain-containing protein 106

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      5056870..5063784
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3ULM0.1 GenPept UniProtKB/Swiss-Prot:Q3ULM0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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