R107.2 ATP-dependent (S)-NAD(P)H-hydrate dehydratase [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: R107.2
Official Full Name: ATP-dependent (S)-NAD(P)H-hydrate dehydratase
Primary source: WormBase:WBGene00011298
Locus tag: CELE_R107.2
See related: AllianceGenome:WB:WBGene00011298
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable ATP-dependent NAD(P)H-hydrate dehydratase activity. Predicted to be involved in metabolite repair. Orthologous to human NAXD (NAD(P)HX dehydratase). [provided by Alliance of Genome Resources, Oct 2024]
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Genomic context

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See R107.2 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 5

Sequence:: Chromosome: III; NC_003281.10 (9043886..9045938, complement)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

R107.2 (e-PCR)
- UniSTS:314820

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP-dependent NAD(P)H-hydrate dehydratase activity	IBA Inferred from Biological aspect of Ancestor more info
enables ATP-dependent NAD(P)H-hydrate dehydratase activity	IEA Inferred from Electronic Annotation more info
enables hydro-lyase activity	IEA Inferred from Electronic Annotation more info
enables lyase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in metabolite repair	IBA Inferred from Biological aspect of Ancestor more info
involved_in nicotinamide nucleotide metabolic process	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ATP-dependent (S)-NAD(P)H-hydrate dehydratase

NP_499001.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

9043886..9045938 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_066600.6 → NP_499001.1 ATP-dependent (S)-NAD(P)H-hydrate dehydratase [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_499001.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P32740

Conserved Domains (1) summary

pfam01256
Location:23 → 286

Carb_kinase; Carbohydrate kinase