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    RBFOX3 RNA binding fox-1 homolog 3 [ Homo sapiens (human) ]

    Gene ID: 146713, updated on 2-Nov-2024

    Summary

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    Official Symbol
    RBFOX3provided by HGNC
    Official Full Name
    RNA binding fox-1 homolog 3provided by HGNC
    Primary source
    HGNC:HGNC:27097
    See related
    Ensembl:ENSG00000167281 MIM:616999; AllianceGenome:HGNC:27097
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    FOX3; NEUN; FOX-3; HRNBP3
    Summary
    This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2017]
    Expression
    Biased expression in brain (RPKM 11.3), prostate (RPKM 4.9) and 4 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See RBFOX3 in Genome Data Viewer
    Location:
    17q25.3
    Exon count:
    39
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (79089345..79665571, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (79984286..80563418, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (77085427..77632826, complement)

    Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9078 Neighboring gene C1QTNF1 antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77040047-77040547 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr17:77042736-77043935 Neighboring gene Sharpr-MPRA regulatory region 5335 Neighboring gene C1q and TNF related 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9079 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77094193-77094906 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77099175-77100160 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77112846-77113750 Neighboring gene endo-beta-N-acetylglucosaminidase Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77157651-77158151 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:77173286-77173965 Neighboring gene uncharacterized LOC124904069 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77179359-77180239 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9080 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:77188893-77189550 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77198565-77199383 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:77207229-77207739 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77219238-77219738 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77219739-77220239 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:77223705-77224476 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12916 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77362366-77362866 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:77369816-77369979 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:77397348-77397522 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77400039-77400540 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77403781-77404282 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77404283-77404782 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77409324-77409841 Neighboring gene Sharpr-MPRA regulatory region 4769 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77505025-77505682 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77528471-77529242 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77529243-77530014 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77544533-77545032 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77645285-77645791 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77655553-77656543 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77657995-77658740 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:77665156-77666000 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_47566 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:77669291-77669891 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12917 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77673338-77673922 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77675499-77676019 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:77680917-77681538 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:77681539-77682160 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77684903-77685452 Neighboring gene long intergenic non-protein coding RNA 2078 Neighboring gene microRNA 4739

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Transforming Growth Factor-β-Induced RBFOX3 Inhibition Promotes Epithelial-Mesenchymal Transition of Lung Cancer Cells. Kim YE, et al. Mol Cells, 2016 Aug 31. PMID 27432190, Free PMC Article
    2. RBFOX3 Regulates the Chemosensitivity of Cancer Cells to 5-Fluorouracil via the PI3K/AKT, EMT and Cytochrome-C/Caspase Pathways. Liu T, et al. Cell Physiol Biochem, 2018. PMID 29689552
    3. Genetic variants in RBFOX3 are associated with sleep latency. Amin N, et al. Eur J Hum Genet, 2016 Oct. PMID 27142678, Free PMC Article
    4. [NeuN nuclear protein in neurons of human brain substantia nigra]. Sukhorukova EG. Morfologiia, 2013. PMID 23898728
    5. NeuN, a DNA-binding neuron-specific protein expressed by Merkel cell carcinoma: analysis of 15 cases. Ungari M, et al. Pathologica, 2021 Dec. PMID 34974547, Free PMC Article

    See all (47) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Paclitaxel-induced inhibition of NSCLC invasion and migration via RBFOX3-mediated circIGF1R biogenesis.
      Title: Paclitaxel-induced inhibition of NSCLC invasion and migration via RBFOX3-mediated circIGF1R biogenesis.
    2. Differential Clinical Features in Colombian Patients With Rolandic Epilepsy and Suggestion of Unlikely Association With GRIN2A, RBFOX1, or RBFOX3 Gene Variants.
      Title: Differential Clinical Features in Colombian Patients With Rolandic Epilepsy and Suggestion of Unlikely Association With GRIN2A, RBFOX1, or RBFOX3 Gene Variants.
    3. Altered temporal sequence of transcriptional regulators in the generation of human cerebellar granule cells.
      Title: Altered temporal sequence of transcriptional regulators in the generation of human cerebellar granule cells.
    4. NeuN, a DNA-binding neuron-specific protein expressed by Merkel cell carcinoma: analysis of 15 cases.
      Title: NeuN, a DNA-binding neuron-specific protein expressed by Merkel cell carcinoma: analysis of 15 cases.
    5. Genetic variants in splicing factor genes and susceptibility to bladder cancer.
      Title: Genetic variants in splicing factor genes and susceptibility to bladder cancer.
    6. RBFOX3 knockdown synergized with 5-FU to inhibit the growth and invasion of HCC cells through PI3K/AKT and epithelial-mesenchymal transition (EMT) signaling, and promote apoptosis by activating the cytochrome-c/caspase signaling pathway.
      Title: RBFOX3 Regulates the Chemosensitivity of Cancer Cells to 5-Fluorouracil via the PI3K/AKT, EMT and Cytochrome-C/Caspase Pathways.
    7. In human lung tissue, Claudin-1 is higher in RBFOX3-positive cells than in RBFOX3-negative cells. Immunostaining and mRNA quantification revealed that protein levels, but not mRNA levels, of Claudin-1 are increased by RBFOX3.
      Title: RBFOX3 regulates Claudin-1 expression in human lung tissue via attenuation of proteasomal degradation.
    8. SNPs (rs9900428, rs9907432 and rs7211029) in RBFOX3 associate with sleep latency.
      Title: Genetic variants in RBFOX3 are associated with sleep latency.
    9. this study show that TGF-beta-induced RBFOX3 inhibition plays an important role in epithelial-mesenchymal transition and lung cancer progression
      Title: Transforming Growth Factor-β-Induced RBFOX3 Inhibition Promotes Epithelial-Mesenchymal Transition of Lung Cancer Cells.
    10. NeuN was recently eventually identified as an epitope of Rbfox3. NeuN is highly conserved among species and is stably expressed during specific stages of development. NeuN has been considered to be a reliable marker of mature neurons, however, this role has been challenged by recent studies indicating that NeuN staining is variable and even absent during certain diseases and states. Review.
      Title: Novel Insights into NeuN: from Neuronal Marker to Splicing Regulator.
    Submit: New GeneRIF Correction See all GeneRIFs (18)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    HIV-1 interactions

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    Protein interactions

    Protein Gene Interaction Pubs
    Tat tat HIV-1 Tat downregulates the expression of RBFOX3/NEUN in human neurons PubMed

    Go to the HIV-1, Human Interaction Database

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ44838, FLJ56884, FLJ58356, MGC176616

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in nervous system development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of alternative mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    RNA binding protein fox-1 homolog 3
    Names
    RNA binding protein, fox-1 homolog 3
    fox-1 homolog C
    hexaribonucleotide binding protein 3
    neuN antigen
    neuronal nuclei antigen

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_053112.2 RefSeqGene

      Range
      59520..581226
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001082575.3 → NP_001076044.1  RNA binding protein fox-1 homolog 3 isoform 1

      See identical proteins and their annotated locations for NP_001076044.1

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624
      Consensus CDS
      CCDS45805.1
      UniProtKB/Swiss-Prot
      A6NFN3, B4DEG6, B4DF29
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Related
      ENSP00000463653.1, ENST00000580155.5
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 297
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    2. NM_001350451.2 → NP_001337380.1  RNA binding protein fox-1 homolog 3 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS92410.1
      UniProtKB/TrEMBL
      A0A3B3ITL7, A0A8I5KWJ3
      Related
      ENSP00000510395.1, ENST00000693108.1
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    3. NM_001350453.2 → NP_001337382.1  RNA binding protein fox-1 homolog 3 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS45805.1
      UniProtKB/Swiss-Prot
      A6NFN3, B4DEG6, B4DF29
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 297
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    4. NM_001385804.1 → NP_001372733.1  RNA binding protein fox-1 homolog 3 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    5. NM_001385805.1 → NP_001372734.1  RNA binding protein fox-1 homolog 3 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    6. NM_001385806.1 → NP_001372735.1  RNA binding protein fox-1 homolog 3 isoform 4

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (4) summary
      PRK13335
      Location:24 → 85
      PRK13335; superantigen-like protein SSL3; Reviewed
      COG0724
      Location:71 → 231
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:207 → 343
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:98 → 173
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    7. NM_001385807.1 → NP_001372736.1  RNA binding protein fox-1 homolog 3 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS92410.1
      UniProtKB/TrEMBL
      A0A3B3ITL7, A0A8I5KWJ3
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    8. NM_001385808.1 → NP_001372737.1  RNA binding protein fox-1 homolog 3 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624
      Consensus CDS
      CCDS92410.1
      UniProtKB/TrEMBL
      A0A3B3ITL7, A0A8I5KWJ3
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    9. NM_001385809.1 → NP_001372738.1  RNA binding protein fox-1 homolog 3 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS92410.1
      UniProtKB/TrEMBL
      A0A3B3ITL7, A0A8I5KWJ3
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    10. NM_001385810.1 → NP_001372739.1  RNA binding protein fox-1 homolog 3 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624
      Consensus CDS
      CCDS92410.1
      UniProtKB/TrEMBL
      A0A3B3ITL7, A0A8I5KWJ3
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    11. NM_001385811.1 → NP_001372740.1  RNA binding protein fox-1 homolog 3 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624
      Consensus CDS
      CCDS92410.1
      UniProtKB/TrEMBL
      A0A3B3ITL7, A0A8I5KWJ3
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    12. NM_001385812.1 → NP_001372741.1  RNA binding protein fox-1 homolog 3 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624
      Consensus CDS
      CCDS92410.1
      UniProtKB/TrEMBL
      A0A3B3ITL7, A0A8I5KWJ3
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    13. NM_001385813.1 → NP_001372742.1  RNA binding protein fox-1 homolog 3 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS92410.1
      UniProtKB/TrEMBL
      A0A3B3ITL7, A0A8I5KWJ3
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    14. NM_001385814.1 → NP_001372743.1  RNA binding protein fox-1 homolog 3 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS92410.1
      UniProtKB/TrEMBL
      A0A3B3ITL7, A0A8I5KWJ3
      Related
      ENSP00000497797.1, ENST00000648001.1
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    15. NM_001385815.1 → NP_001372744.1  RNA binding protein fox-1 homolog 3 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS92410.1
      UniProtKB/TrEMBL
      A0A3B3ITL7, A0A8I5KWJ3
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    16. NM_001385816.1 → NP_001372745.1  RNA binding protein fox-1 homolog 3 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS92410.1
      UniProtKB/TrEMBL
      A0A3B3ITL7, A0A8I5KWJ3
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    17. NM_001385817.1 → NP_001372746.1  RNA binding protein fox-1 homolog 3 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS92410.1
      UniProtKB/TrEMBL
      A0A3B3ITL7, A0A8I5KWJ3
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    18. NM_001385818.1 → NP_001372747.1  RNA binding protein fox-1 homolog 3 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS92410.1
      UniProtKB/TrEMBL
      A0A3B3ITL7, A0A8I5KWJ3
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    19. NM_001385819.1 → NP_001372748.1  RNA binding protein fox-1 homolog 3 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS92410.1
      UniProtKB/TrEMBL
      A0A3B3ITL7, A0A8I5KWJ3
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    20. NM_001385820.1 → NP_001372749.1  RNA binding protein fox-1 homolog 3 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS92410.1
      UniProtKB/TrEMBL
      A0A3B3ITL7, A0A8I5KWJ3
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    21. NM_001385821.1 → NP_001372750.1  RNA binding protein fox-1 homolog 3 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS92410.1
      UniProtKB/TrEMBL
      A0A3B3ITL7, A0A8I5KWJ3
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    22. NM_001385822.1 → NP_001372751.1  RNA binding protein fox-1 homolog 3 isoform 5

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS92408.1
      UniProtKB/TrEMBL
      A0A3B3ITL7, J3QRF4
      Related
      ENSP00000464186.1, ENST00000583458.5
      Conserved Domains (4) summary
      PRK13335
      Location:24 → 85
      PRK13335; superantigen-like protein SSL3; Reviewed
      COG0724
      Location:71 → 231
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:207 → 343
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:98 → 173
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    23. NM_001385823.1 → NP_001372752.1  RNA binding protein fox-1 homolog 3 isoform 5

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS92408.1
      UniProtKB/TrEMBL
      A0A3B3ITL7, J3QRF4
      Conserved Domains (4) summary
      PRK13335
      Location:24 → 85
      PRK13335; superantigen-like protein SSL3; Reviewed
      COG0724
      Location:71 → 231
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:207 → 343
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:98 → 173
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    24. NM_001385824.1 → NP_001372753.1  RNA binding protein fox-1 homolog 3 isoform 6

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS92409.1
      UniProtKB/TrEMBL
      A0A3B3ITL7, J3QQZ2
      Related
      ENSP00000463964.1, ENST00000582043.5
      Conserved Domains (3) summary
      COG0724
      Location:27 → 133
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:177 → 313
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cl17169
      Location:99 → 138
      RRM_SF; RNA recognition motif (RRM) superfamily

    25. NM_001385825.1 → NP_001372754.1  RNA binding protein fox-1 homolog 3 isoform 7

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Related
      ENSP00000462007.1, ENST00000584778.5
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 297
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    26. NM_001385826.1 → NP_001372755.1  RNA binding protein fox-1 homolog 3 isoform 7

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 297
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    27. NM_001385827.1 → NP_001372756.1  RNA binding protein fox-1 homolog 3 isoform 9

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 239
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:215 → 304
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    28. NM_001385828.1 → NP_001372757.1  RNA binding protein fox-1 homolog 3 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS45805.1
      UniProtKB/Swiss-Prot
      A6NFN3, B4DEG6, B4DF29
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 297
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    29. NM_001385829.1 → NP_001372758.1  RNA binding protein fox-1 homolog 3 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624
      Consensus CDS
      CCDS45805.1
      UniProtKB/Swiss-Prot
      A6NFN3, B4DEG6, B4DF29
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 297
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    30. NM_001385830.1 → NP_001372759.1  RNA binding protein fox-1 homolog 3 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS45805.1
      UniProtKB/Swiss-Prot
      A6NFN3, B4DEG6, B4DF29
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 297
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    31. NM_001385831.1 → NP_001372760.1  RNA binding protein fox-1 homolog 3 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS45805.1
      UniProtKB/Swiss-Prot
      A6NFN3, B4DEG6, B4DF29
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 297
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    32. NM_001385832.1 → NP_001372761.1  RNA binding protein fox-1 homolog 3 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624
      Consensus CDS
      CCDS45805.1
      UniProtKB/Swiss-Prot
      A6NFN3, B4DEG6, B4DF29
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 297
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    33. NM_001385833.1 → NP_001372762.1  RNA binding protein fox-1 homolog 3 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS45805.1
      UniProtKB/Swiss-Prot
      A6NFN3, B4DEG6, B4DF29
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 297
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    34. NM_001385834.1 → NP_001372763.1  RNA binding protein fox-1 homolog 3 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624
      Consensus CDS
      CCDS45805.1
      UniProtKB/Swiss-Prot
      A6NFN3, B4DEG6, B4DF29
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 297
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    35. NM_001385835.1 → NP_001372764.1  RNA binding protein fox-1 homolog 3 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624
      Consensus CDS
      CCDS45805.1
      UniProtKB/Swiss-Prot
      A6NFN3, B4DEG6, B4DF29
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 297
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    36. NM_001385836.1 → NP_001372765.1  RNA binding protein fox-1 homolog 3 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS45805.1
      UniProtKB/Swiss-Prot
      A6NFN3, B4DEG6, B4DF29
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 297
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    37. NM_001385837.1 → NP_001372766.1  RNA binding protein fox-1 homolog 3 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624
      Consensus CDS
      CCDS45805.1
      UniProtKB/Swiss-Prot
      A6NFN3, B4DEG6, B4DF29
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 297
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    38. NM_001385838.1 → NP_001372767.1  RNA binding protein fox-1 homolog 3 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS45805.1
      UniProtKB/Swiss-Prot
      A6NFN3, B4DEG6, B4DF29
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 297
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    39. NM_001385839.1 → NP_001372768.1  RNA binding protein fox-1 homolog 3 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS45805.1
      UniProtKB/Swiss-Prot
      A6NFN3, B4DEG6, B4DF29
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 297
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    40. NM_001385840.1 → NP_001372769.1  RNA binding protein fox-1 homolog 3 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS45805.1
      UniProtKB/Swiss-Prot
      A6NFN3, B4DEG6, B4DF29
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 297
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    41. NM_001385841.1 → NP_001372770.1  RNA binding protein fox-1 homolog 3 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS45805.1
      UniProtKB/Swiss-Prot
      A6NFN3, B4DEG6, B4DF29
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 297
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    42. NM_001385842.1 → NP_001372771.1  RNA binding protein fox-1 homolog 3 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Consensus CDS
      CCDS45805.1
      UniProtKB/Swiss-Prot
      A6NFN3, B4DEG6, B4DF29
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 297
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    43. NM_001385843.1 → NP_001372772.1  RNA binding protein fox-1 homolog 3 isoform 8

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      TIGR01661
      Location:25 → 169
      ELAV_HUD_SF; ELAV/HuD family splicing factor
      pfam12414
      Location:207 → 296
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:98 → 173
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    44. NM_001385844.1 → NP_001372773.1  RNA binding protein fox-1 homolog 3 isoform 8

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      TIGR01661
      Location:25 → 169
      ELAV_HUD_SF; ELAV/HuD family splicing factor
      pfam12414
      Location:207 → 296
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:98 → 173
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    45. NM_001385845.1 → NP_001372774.1  RNA binding protein fox-1 homolog 3 isoform 8

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      TIGR01661
      Location:25 → 169
      ELAV_HUD_SF; ELAV/HuD family splicing factor
      pfam12414
      Location:207 → 296
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:98 → 173
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    46. NM_001385846.1 → NP_001372775.1  RNA binding protein fox-1 homolog 3 isoform 8

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      TIGR01661
      Location:25 → 169
      ELAV_HUD_SF; ELAV/HuD family splicing factor
      pfam12414
      Location:207 → 296
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:98 → 173
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    47. NM_001385847.1 → NP_001372776.1  RNA binding protein fox-1 homolog 3 isoform 10

      Status: REVIEWED

      Source sequence(s)
      AC020689, AC021534, AC055858, AC073624, AC233701
      Conserved Domains (3) summary
      PRK10927
      Location:23 → 155
      PRK10927; cell division protein FtsN
      pfam12414
      Location:159 → 248
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cl17169
      Location:99 → 120
      RRM_SF; RNA recognition motif (RRM) superfamily

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

      Range
      79089345..79665571 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047435405.1 → XP_047291361.1  RNA binding protein fox-1 homolog 3 isoform X5

    2. XM_017024211.3 → XP_016879700.1  RNA binding protein fox-1 homolog 3 isoform X5

      Conserved Domains (3) summary
      COG0724
      Location:27 → 133
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:177 → 266
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cl17169
      Location:99 → 138
      RRM_SF; RNA recognition motif (RRM) superfamily

    3. XM_024450593.2 → XP_024306361.1  RNA binding protein fox-1 homolog 3 isoform X1

      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    4. XM_024450592.2 → XP_024306360.1  RNA binding protein fox-1 homolog 3 isoform X1

      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    5. XM_017024208.2 → XP_016879697.1  RNA binding protein fox-1 homolog 3 isoform X1

      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    6. XM_011524366.3 → XP_011522668.1  RNA binding protein fox-1 homolog 3 isoform X3

      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      PRK13335
      Location:24 → 85
      PRK13335; superantigen-like protein SSL3; Reviewed
      smart00360
      Location:99 → 169
      RRM; RNA recognition motif
      COG0724
      Location:71 → 231
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

    7. XM_011524367.3 → XP_011522669.1  RNA binding protein fox-1 homolog 3 isoform X4

      Conserved Domains (3) summary
      COG0724
      Location:27 → 133
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:177 → 266
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cl17169
      Location:99 → 138
      RRM_SF; RNA recognition motif (RRM) superfamily

    8. XM_017024209.2 → XP_016879698.1  RNA binding protein fox-1 homolog 3 isoform X2

      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 133
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:177 → 313
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cl17169
      Location:99 → 138
      RRM_SF; RNA recognition motif (RRM) superfamily

    9. XM_011524360.2 → XP_011522662.1  RNA binding protein fox-1 homolog 3 isoform X1

      See identical proteins and their annotated locations for XP_011522662.1

      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    10. XM_024450596.2 → XP_024306364.1  RNA binding protein fox-1 homolog 3 isoform X1

      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    11. XM_024450595.2 → XP_024306363.1  RNA binding protein fox-1 homolog 3 isoform X1

      UniProtKB/TrEMBL
      A0A3B3ITL7
      Conserved Domains (3) summary
      COG0724
      Location:27 → 232
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:208 → 344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:99 → 174
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060941.1 Alternate T2T-CHM13v2.0

      Range
      79984286..80563418 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054315132.1 → XP_054171107.1  RNA binding protein fox-1 homolog 3 isoform X5

    2. XM_054315131.1 → XP_054171106.1  RNA binding protein fox-1 homolog 3 isoform X5

    3. XM_054315122.1 → XP_054171097.1  RNA binding protein fox-1 homolog 3 isoform X1

    4. XM_054315125.1 → XP_054171100.1  RNA binding protein fox-1 homolog 3 isoform X1

    5. XM_054315127.1 → XP_054171102.1  RNA binding protein fox-1 homolog 3 isoform X1

    6. XM_054315129.1 → XP_054171104.1  RNA binding protein fox-1 homolog 3 isoform X3

    7. XM_054315130.1 → XP_054171105.1  RNA binding protein fox-1 homolog 3 isoform X4

    8. XM_054315128.1 → XP_054171103.1  RNA binding protein fox-1 homolog 3 isoform X2

    9. XM_054315126.1 → XP_054171101.1  RNA binding protein fox-1 homolog 3 isoform X1

    10. XM_054315124.1 → XP_054171099.1  RNA binding protein fox-1 homolog 3 isoform X1

    11. XM_054315123.1 → XP_054171098.1  RNA binding protein fox-1 homolog 3 isoform X1

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001025448.1: Suppressed sequence

      Description
      NM_001025448.1: This RefSeq was permanently suppressed because it contains the wrong CDS.

    2. NM_001039904.1: Suppressed sequence

      Description
      NM_001039904.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A6NFN3.4 GenPept UniProtKB/Swiss-Prot:A6NFN3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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