Crip1 cysteine-rich protein 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Crip1provided by MGI
Official Full Name: cysteine-rich protein 1provided by MGI
Primary source: MGI:MGI:88501
See related: Ensembl:ENSMUSG00000006360 AllianceGenome:MGI:88501
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: CRHP; CRP1; Crip
Summary: Predicted to enable peptide binding activity and zinc ion binding activity. Predicted to be involved in several processes, including cellular response to UV-B; intrinsic apoptotic signaling pathway in response to DNA damage; and response to zinc ion. Predicted to be located in cytoplasm. Is expressed in several structures, including genitourinary system; gut; hemolymphoid system gland; integumental system; and limb segment. Orthologous to human CRIP1 (cysteine rich protein 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in large intestine adult (RPKM 3684.4), small intestine adult (RPKM 2998.6) and 10 other tissues See more
Orthologs: human all
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Genomic context

Location:: 12 F1; 12 61.59 cM

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	12	NC_000078.7 (113115632..113117499)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	12	NC_000078.6 (113152012..113153879)

Chromosome 12 - NC_000078.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH133355 (e-PCR)
- UniSTS:216638

Crip (e-PCR), detects polymorphism
- UniSTS:141399

RH136592 (e-PCR)
- UniSTS:210572

D10Bir4 (e-PCR), detects polymorphism
- UniSTS:141484

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables peptide binding	ISO Inferred from Sequence Orthology more info
enables peptide binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables zinc ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables zinc ion binding	ISO Inferred from Sequence Orthology more info
enables zinc ion binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in cellular response to UV-B	ISO Inferred from Sequence Orthology more info
involved_in cellular response to UV-B	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in cellular response to antibiotic	ISO Inferred from Sequence Orthology more info
involved_in cellular response to antibiotic	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in intrinsic apoptotic signaling pathway in response to DNA damage	IBA Inferred from Biological aspect of Ancestor more info
involved_in intrinsic apoptotic signaling pathway in response to DNA damage	ISO Inferred from Sequence Orthology more info
involved_in intrinsic apoptotic signaling pathway in response to DNA damage	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in regulation of gene expression	IBA Inferred from Biological aspect of Ancestor more info
involved_in response to zinc ion	ISO Inferred from Sequence Orthology more info
involved_in response to zinc ion	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info	PubMed

General protein information

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Preferred Names: cysteine-rich protein 1

Names: CRP-1; cysteine-rich intestinal protein; cysteine-rich protein 1 (intestinal)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.