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    Rps25 ribosomal protein s25 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 122799, updated on 17-Aug-2024

    Summary

    Official Symbol
    Rps25provided by RGD
    Official Full Name
    ribosomal protein s25provided by RGD
    Primary source
    RGD:621043
    See related
    EnsemblRapid:ENSRNOG00000027503 AllianceGenome:RGD:621043
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    A structural constituent of ribosome. Involved in cellular response to amino acid starvation and ribosomal small subunit assembly. Located in nucleus. Part of cytosolic small ribosomal subunit and polysome. Orthologous to human RPS25 (ribosomal protein S25). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Spleen (RPKM 3811.2), Thymus (RPKM 3485.6) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Rps25 in Genome Data Viewer
    Location:
    8q22
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (53630333..53632810)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (44733623..44735999)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (48727346..48729722)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 37 member 4 Neighboring gene trafficking protein particle complex subunit 4 Neighboring gene centrosomal AT-AC splicing factor Neighboring gene methyltransferase like 9, pseudogene 1 Neighboring gene forkhead box R1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cellular response to amino acid starvation IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in rRNA processing ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ribosomal small subunit assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in ribosomal small subunit biogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of cytosolic small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
     
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in synapse ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    small ribosomal subunit protein eS25
    Names
    40S ribosomal protein S25

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005528.2NP_001005528.1  small ribosomal subunit protein eS25

      See identical proteins and their annotated locations for NP_001005528.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/Swiss-Prot
      P62853, Q3SYP7
      UniProtKB/TrEMBL
      A6J3Z0, F1M6F4
      Related
      ENSRNOP00000033144.7, ENSRNOT00000029546.7
      Conserved Domains (1) summary
      pfam03297
      Location:19111
      Ribosomal_S25; S25 ribosomal protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      53630333..53632810
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063264797.1XP_063120867.1  small ribosomal subunit protein eS25 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZLX3