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    Cea carcinoembryonic antigen gene family [ Mus musculus (house mouse) ]

    Gene ID: 111518, updated on 17-Aug-2024

    Summary

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    Official Symbol
    Ceaprovided by MGI
    Official Full Name
    carcinoembryonic antigen gene familyprovided by MGI
    Primary source
    MGI:MGI:88365
    Gene type
    other
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Annotation information
    not in current annotation release
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    Genomic context

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    Location:
    chromosome: 7

    Bibliography

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    Related articles in PubMed

    1. Elevated levels of CA 19-9 and CEA in pancreatic cancer-associated diabetes. Guo Q, et al. J Cancer Res Clin Oncol, 2010 Nov. PMID 20174821
    2. Ubiquitous nuclear factors bind specifically to a 5'-region conserved in carcinoembryonic antigen-related genes. Rudert F, et al. Biochem Biophys Res Commun, 1992 Jun 30. PMID 1627143
    3. Characterization of antigen-specific immune responses induced by canarypox virus vaccines. Bos R, et al. J Immunol, 2007 Nov 1. PMID 17947686
    4. Colorectal hyperplasia and dysplasia due to human carcinoembryonic antigen (CEA) family member expression in transgenic mice. Chan CH, et al. PLoS One, 2007 Dec 26. PMID 18159236, Free PMC Article
    5. A strategy for blood biomarker amplification and localization using ultrasound. D'Souza AL, et al. Proc Natl Acad Sci U S A, 2009 Oct 6. PMID 19805109, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. In a cohort with non-small cell lung cancer, serum CEA levels were abnormally high in 54.3% of the patients. Increasing serum CEA was correlated with tumor EGFR mutation.
      Title: Analysis of CEA expression and EGFR mutation status in non-small cell lung cancers.
    2. upregulated transcription correlates with tumor size in Non-Small-Cell Lung Cancer
      Title: Cytokeratin 19, carcinoembryonic antigen, and epithelial cell adhesion molecule detect lung cancer lymph node metastasis in endobronchial ultrasound-guided transbronchial aspiration samples.
    3. Data indicate that serum carcino-embryonic antigen (CEA) has a tendency to increase over time in patients with urinary diversion (UD) but is not a valuable marker of secondary neoplasms in these patients.
      Title: Serum carcino-embryonic antigen (CEA) and its possible use as tumor marker for secondary tumors in urinary intestinal reservoirs.
    4. Findings suggested the possible role of carcinoembryonic antigen (CEA) in the pathogenesis of brain invasion.
      Title: The relevance of serum carcinoembryonic antigen as an indicator of brain metastasis detection in advanced non-small cell lung cancer.
    5. CEA mRNA, CK20 mRNA, and serum CEA than patients at stages I-III.
      Title: Comparative analysis of tumor markers and evaluation of their predictive value in patients with colorectal cancer.
    6. CEA acts to promote the metastatic dissemination of tumor cells. On depletion of CEA, the metastatic potential of LS174T cells is dramatically reduced.
      Title: Divergent roles of CD44 and carcinoembryonic antigen in colon cancer metastasis.
    7. preoperative expression level is a prognostic factor in patients with stage I non-small cell lung cancer
      Title: Preoperative CYFRA 21-1 and CEA as prognostic factors in patients with stage I non-small cell lung cancer.
    8. The significant expression of IMP3 and CEA in less well-differentiated foci of mucinous MDA may be helpful in the diagnosis of mucinous MDA to some extent.
      Title: Expression of the insulin-like growth factor-II mRNA-binding protein 3 (IMP3) and carcinoembryonic antigen (CEA) in mucinous minimal deviation adenocarcinoma.
    9. Vaccination with the plasmid for the triple repeated CEA peptides induced stronger Th1 responses
      Title: DNA vaccine expressing repeated carcinoembryonic antigen (CEA)(625-667) induces strong immunity in mice.
    10. Elevated levels of CEA are associated with pancreatic cancer and new-onset diabetes.
      Title: Elevated levels of CA 19-9 and CEA in pancreatic cancer-associated diabetes.
    Submit: New GeneRIF Correction See all GeneRIFs (13)

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