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    Polq DNA polymerase theta [ Nannospalax galili (Upper Galilee mountains blind mole rat) ]

    Gene ID: 103741960, updated on 11-Mar-2024

    Summary

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    Gene symbol
    Polq
    Gene description
    DNA polymerase theta
    See related
    Ensembl:ENSNGAG00000024216
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Nannospalax galili
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Spalacidae; Spalacinae; Nannospalax
    Orthologs
    human mouse all
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    Genomic context

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    See Polq in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    102 current S.galili_v1.0 (GCF_000622305.1) Unplaced Scaffold NW_008346548.1 (8540842..8665418, complement)

    NW_008346548.1Genomic Context describing neighboring genes Neighboring gene syntaxin binding protein 5L Neighboring gene U1 spliceosomal RNA Neighboring gene acid ceramidase-like Neighboring gene F-box protein 40 Neighboring gene hematopoietic cell-specific Lyn substrate 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_008346548 Unplaced Scaffold Reference S.galili_v1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA-directed DNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in double-strand break repair via alternative nonhomologous end joining IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA polymerase theta
    Names
    polymerase (DNA directed), theta

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Nannospalax galili Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference S.galili_v1.0 Primary Assembly

    Genomic

    1. NW_008346548.1 Reference S.galili_v1.0 Primary Assembly

      Range
      8540842..8665418 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_029568225.1 → XP_029424085.1  DNA polymerase theta isoform X2

      UniProtKB/TrEMBL
      A0A8C6S2G6
      Related
      ENSNGAP00000026627.1, ENSNGAT00000032359.1
      Conserved Domains (4) summary
      cd08638
      Location:2079 → 2572
      DNA_pol_A_theta; DNA polymerase theta is a low-fidelity family A enzyme implicated in translesion synthesis and in somatic hypermutation
      PRK02362
      Location:75 → 822
      PRK02362; ATP-dependent DNA helicase
      cd18026
      Location:75 → 288
      DEXHc_POLQ-like; DEXH-box helicase domain of DNA polymerase theta
      cl10012
      Location:1876 → 2073
      DnaQ_like_exo; DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily

    2. XM_008842915.3 → XP_008841137.1  DNA polymerase theta isoform X1

      UniProtKB/TrEMBL
      A0A8C6S2G6
      Related
      ENSNGAP00000026626.1, ENSNGAT00000032358.1
      Conserved Domains (4) summary
      cd08638
      Location:2089 → 2582
      DNA_pol_A_theta; DNA polymerase theta is a low-fidelity family A enzyme implicated in translesion synthesis and in somatic hypermutation
      COG1204
      Location:75 → 829
      BRR2; Replicative superfamily II helicase [Replication, recombination and repair]
      cd18026
      Location:75 → 288
      DEXHc_POLQ-like; DEXH-box helicase domain of DNA polymerase theta
      cl10012
      Location:1886 → 2083
      DnaQ_like_exo; DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily

    3. XM_029568226.1 → XP_029424086.1  DNA polymerase theta isoform X3

      UniProtKB/TrEMBL
      A0A8C6S2G6
      Conserved Domains (3) summary
      COG1204
      Location:75 → 829
      BRR2; Replicative superfamily II helicase [Replication, recombination and repair]
      PRK05755
      Location:1892 → 2155
      PRK05755; DNA polymerase I; Provisional
      cd18026
      Location:75 → 288
      DEXHc_POLQ-like; DEXH-box helicase domain of DNA polymerase theta
    Nucleotide Protein
    Heading Accession and Version

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