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    SOCS1 suppressor of cytokine signaling 1 [ Equus caballus (horse) ]

    Gene ID: 102148488, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SOCS1provided by VGNC
    Official Full Name
    suppressor of cytokine signaling 1provided by VGNC
    Primary source
    VGNC:VGNC:23437
    See related
    Ensembl:ENSECAG00000026965
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See SOCS1 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 13 NC_009156.3 (34388608..34390451)

    Chromosome 13 - NC_009156.3Genomic Context describing neighboring genes Neighboring gene protamine 3 Neighboring gene transition protein 2 Neighboring gene uncharacterized LOC111767567 Neighboring gene C-type lectin domain containing 16A Neighboring gene Dexi homolog

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009156.3 Chromosome 13 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol-3-kinase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of phosphatidylinositol 3-kinase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    suppressor of cytokine signaling 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009156.3 Reference EquCab3.0 Primary Assembly

      Range
      34388608..34390451
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023616313.1 → XP_023472081.1  suppressor of cytokine signaling 1

      UniProtKB/TrEMBL
      F6SF14
      Related
      ENSECAP00000022763.2, ENSECAT00000028923.3
      Conserved Domains (2) summary
      cd10382
      Location:79 → 176
      SH2_SOCS1; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
      cl02533
      Location:180 → 222
      SOCS; SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/SOCS family proteins (in combination with a SH2 domain), ASBs (ankyrin repeat-containing proteins with a SOCS box), SSBs (SPRY domain-containing proteins ...
    Nucleotide Protein
    Heading Accession and Version

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