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    MAPK1 mitogen-activated protein kinase 1 [ Felis catus (domestic cat) ]

    Gene ID: 101087614, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MAPK1
    Official Full Name
    mitogen-activated protein kinase 1
    Primary source
    VGNC:VGNC:68163
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Felis catus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
    Orthologs
    human mouse all
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    Genomic context

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    See MAPK1 in Genome Data Viewer
    Location:
    chromosome: D3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) D3 NC_058379.1 (29458187..29565208, complement)
    104 previous assembly Felis_catus_9.0 (GCF_000181335.3) D3 NC_018734.3 (30215808..30327824, complement)

    Chromosome D3 - NC_058379.1Genomic Context describing neighboring genes Neighboring gene peptidylprolyl isomerase like 2 Neighboring gene yippee like 1 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC123381202 Neighboring gene uncharacterized LOC109493304 Neighboring gene protein phosphatase, Mg2+/Mn2+ dependent 1F

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. JNK activation is essential for activation of MEK/ERK signaling in IL-1β-induced COX-2 expression in synovial fibroblasts. Kitanaka T, et al. Sci Rep, 2017 Jan 5. PMID 28054591, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables MAP kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitogen-activated protein kinase 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference F.catus_Fca126_mat1.0 Primary Assembly

    Genomic

    1. NC_058379.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

      Range
      29458187..29565208 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003994973.5 → XP_003995022.1  mitogen-activated protein kinase 1

      See identical proteins and their annotated locations for XP_003995022.1

      UniProtKB/TrEMBL
      A0A337SUJ5
      Conserved Domains (1) summary
      cd07849
      Location:19 → 353
      STKc_ERK1_2_like; Catalytic domain of Extracellular signal-Regulated Kinase 1 and 2-like Serine/Threonine Kinases
    Nucleotide Protein
    Heading Accession and Version

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