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    Comt catechol-O-methyltransferase [ Cavia porcellus (domestic guinea pig) ]

    Gene ID: 100730509, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Comt
    Gene description
    catechol-O-methyltransferase
    See related
    Ensembl:ENSCPOG00000004445
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cavia porcellus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947499.1 (30235768..30255860)
    103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176415.1 (19032557..19052596)

    NW_026947499.1Genomic Context describing neighboring genes Neighboring gene T-box transcription factor 1 Neighboring gene G protein subunit beta 1 like Neighboring gene thioredoxin reductase 2 Neighboring gene ARVCF delta catenin family member Neighboring gene transport and golgi organization 2 homolog Neighboring gene uncharacterized LOC134470698

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables catechol O-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in catecholamine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in developmental process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in dopamine metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in dendrite IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    catechol O-methyltransferase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mCavPor4.1

    Genomic

    1. NW_026947499.1 Reference mCavPor4.1

      Range
      30235768..30255860
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_013141678.3 → XP_012997132.1  catechol O-methyltransferase

      See identical proteins and their annotated locations for XP_012997132.1

      UniProtKB/TrEMBL
      A0A286XRD6, H0V363
      Related
      ENSCPOP00000027929.1
      Conserved Domains (1) summary
      cl17173
      Location:66 → 233
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

    2. XM_013141679.2 → XP_012997133.1  catechol O-methyltransferase

      See identical proteins and their annotated locations for XP_012997133.1

      UniProtKB/TrEMBL
      A0A286XRD6, H0V363
      Conserved Domains (1) summary
      cl17173
      Location:66 → 233
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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