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    syde2 synapse defective 1, Rho GTPase, homolog 2 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100494956, updated on 4-Nov-2024

    Summary

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    Official Symbol
    syde2provided by Xenbase
    Official Full Name
    synapse defective 1, Rho GTPase, homolog 2provided by Xenbase
    Primary source
    Xenbase:XB-GENE-980337
    See related
    Ensembl:ENSXETG00000008629 AllianceGenome:Xenbase:XB-GENE-980337
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Summary
    Predicted to act upstream of or within signal transduction. Orthologous to human SYDE2 (synapse defective Rho GTPase homolog 2). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See syde2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 4 NC_030680.2 (77252588..77302963)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 4 NC_030680.1 (29233708..29283896)

    Chromosome 4 - NC_030680.2Genomic Context describing neighboring genes Neighboring gene chromosome 4 C1orf52 homolog Neighboring gene BCL10, immune signaling adaptor Neighboring gene dynein axonemal intermediate chain 3 Neighboring gene mucolipin TRP cation channel 3 Neighboring gene lysophosphatidic acid receptor 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Process Evidence Code Pubs
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    rho GTPase-activating protein SYDE2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      77252588..77302963
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002931674.5 → XP_002931720.3  rho GTPase-activating protein SYDE2 isoform X1

      UniProtKB/TrEMBL
      A0A6I8RMF6, F6W5P5
      Related
      ENSXETP00000083368.2, ENSXETT00000073130.2
      Conserved Domains (2) summary
      cl02570
      Location:1176 → 1390
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
      cl14603
      Location:1041 → 1156
      C2; C2 domain

    2. XM_031900844.1 → XP_031756704.1  rho GTPase-activating protein SYDE2 isoform X2

      UniProtKB/TrEMBL
      A0A8J1JFQ3
      Conserved Domains (2) summary
      cl02570
      Location:591 → 805
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
      cl14603
      Location:456 → 571
      C2; C2 domain
    Nucleotide Protein Strain
    Heading Accession and Version

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