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    gria3.L glutamate receptor, ionotropic, AMPA 3 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 100294516, updated on 18-Sep-2024

    Summary

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    Official Symbol
    gria3.L
    Official Full Name
    glutamate receptor, ionotropic, AMPA 3 L homeolog
    Primary source
    Xenbase:XB-GENE-6372209
    Locus tag
    XELAEV_18038771mg
    See related
    EnsemblRapid:ENSXLAG00005014471
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    glur3; gria3
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    Genomic context

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    See gria3.L in Genome Data Viewer
    Location:
    chromosome: 8L
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8L NC_054385.1 (39717806..39910944)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8L NC_030738.1 (26544101..26737956)

    Chromosome 8L - NC_054385.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121397371 Neighboring gene uncharacterized LOC121397024 Neighboring gene THO complex 2 L homeolog Neighboring gene X-linked inhibitor of apoptosis L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Xenopus laevis oocytes endogenously express all subunits of the ionotropic glutamate receptor family. Schmidt C, et al. J Mol Biol, 2009 Jul 10. PMID 19445955

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables AMPA glutamate receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ligand-gated monoatomic ion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within modulation of chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within synaptic transmission, glutamatergic IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of AMPA glutamate receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in dendritic spine IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in postsynaptic density membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    glutamate receptor, ionotropic, AMPA 3 L homeolog
    Names
    glutamate receptor, ionotrophic, AMPA 3
    ionotropic glutamate receptor subunit GluR3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001159682.1 → NP_001153154.1  glutamate receptor, ionotropic, AMPA 3 L homeolog precursor

      See identical proteins and their annotated locations for NP_001153154.1

      Status: PROVISIONAL

      Source sequence(s)
      FJ492191
      UniProtKB/TrEMBL
      B9V8R9
      Conserved Domains (4) summary
      cd13715
      Location:416 → 798
      PBP2_iGluR_AMPA; The ligand-binding domain of the AMPA (alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid) subtypes of ionotropic glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      pfam00060
      Location:548 → 828
      Lig_chan; Ligand-gated ion channel
      pfam01094
      Location:40 → 383
      ANF_receptor; Receptor family ligand binding region
      cl10011
      Location:29 → 400
      Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      39717806..39910944
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018228562.2 → XP_018084051.1  glutamate receptor, ionotropic, AMPA 3 L homeolog isoform X3

      UniProtKB/TrEMBL
      A0A8J0TE11
      Related
      ENSXLAP00005042361.1, ENSXLAT00005043427.1

    2. XM_018228561.2 → XP_018084050.1  glutamate receptor, ionotropic, AMPA 3 L homeolog isoform X2

      UniProtKB/TrEMBL
      A0A1L8F7A8, A0A974H782
      Related
      ENSXLAP00005042366.1, ENSXLAT00005043432.1

    3. XM_041571874.1 → XP_041427808.1  glutamate receptor, ionotropic, AMPA 3 L homeolog isoform X1

      UniProtKB/TrEMBL
      A0A8J1LE43
      Related
      ENSXLAP00005042369.1, ENSXLAT00005043435.1
      Conserved Domains (2) summary
      cd13715
      Location:416 → 798
      PBP2_iGluR_AMPA; The ligand-binding domain of the AMPA (alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid) subtypes of ionotropic glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06387
      Location:29 → 403
      PBP1_iGluR_AMPA_GluR3; N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the GluR3 subunit of the AMPA receptor

    RNA

    1. XR_005963153.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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