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    prl prolactin [ Oncorhynchus mykiss (rainbow trout) ]

    Gene ID: 100136792, updated on 8-Mar-2024

    Summary

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    Gene symbol
    prl
    Gene description
    prolactin
    See related
    Ensembl:ENSOMYG00000024343
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Oncorhynchus mykiss
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Oncorhynchus
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    zebrafish all
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    Genomic context

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    See prl in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    101 current USDA_OmykA_1.1 (GCF_013265735.2) 12 NC_048576.1 (62948706..62952733)
    100 previous assembly Omyk_1.0 (GCF_002163495.1) 12 NC_035088.1 (59598661..59602684)

    Chromosome 12 - NC_048576.1Genomic Context describing neighboring genes Neighboring gene serine/threonine-protein kinase BRSK2 Neighboring gene uncharacterized LOC110537963 Neighboring gene thyroid hormone receptor alpha Neighboring gene vesicle-fusing ATPase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Prolactin peptide (pPRL) induces anti-prolactin antibodies, ROS and cortisol but suppresses specific immune responses in rainbow trout. Villalba M, et al. Mol Immunol, 2020 Nov. PMID 32947170
    2. Rainbow trout prolactin cDNA cloning in Escherichia coli. Mercier L, et al. DNA, 1989 Mar. PMID 2647439
    3. The rainbow trout genome provides novel insights into evolution after whole-genome duplication in vertebrates. Berthelot C, et al. Nat Commun, 2014 Apr 22. PMID 24755649, Free PMC Article
    4. Characterization of the rainbow trout transcriptome using Sanger and 454-pyrosequencing approaches. Salem M, et al. BMC Genomics, 2010 Oct 13. PMID 20942956, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Prolactin peptide (pPRL) induces anti-prolactin antibodies, ROS and cortisol but suppresses specific immune responses in rainbow trout.
      Title: Prolactin peptide (pPRL) induces anti-prolactin antibodies, ROS and cortisol but suppresses specific immune responses in rainbow trout.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables hormone activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of receptor signaling pathway via JAK-STAT IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to nutrient levels IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    prolactin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001124733.1 → NP_001118205.1  prolactin precursor

      See identical proteins and their annotated locations for NP_001118205.1

      Status: PROVISIONAL

      Source sequence(s)
      M24738
      UniProtKB/Swiss-Prot
      P21993
      UniProtKB/TrEMBL
      A0A060WYA2, A0A8C7WL54
      Related
      ENSOMYP00000053184.1, ENSOMYT00000057858.2
      Conserved Domains (1) summary
      cl07831
      Location:26 → 204
      growth_hormone_like; Somatotropin/prolactin hormone family

    RefSeqs of Annotated Genomes: Oncorhynchus mykiss Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference USDA_OmykA_1.1 Primary Assembly

    Genomic

    1. NC_048576.1 Reference USDA_OmykA_1.1 Primary Assembly

      Range
      62948706..62952733
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P21993.1 GenPept UniProtKB/Swiss-Prot:P21993

    Gene LinkOut

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