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    AGT angiotensinogen [ Equus caballus (horse) ]

    Gene ID: 100065526, updated on 17-Aug-2024

    Summary

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    Official Symbol
    AGTprovided by VGNC
    Official Full Name
    angiotensinogenprovided by VGNC
    Primary source
    VGNC:VGNC:50569
    See related
    Ensembl:ENSECAG00000015711
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Also known as
    SERPINA8
    Orthologs
    human mouse all
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    Genomic context

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    See AGT in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 1 NC_009144.3 (67725555..67736364)

    Chromosome 1 - NC_009144.3Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S13-like Neighboring gene 40S ribosomal protein S13-like Neighboring gene component of oligomeric golgi complex 2 Neighboring gene DNA-directed RNA polymerase III subunit RPC10 pseudogene

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009144.3 Chromosome 1 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of systemic arterial blood pressure by renin-angiotensin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    angiotensinogen
    Names
    Serpin A8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009144.3 Reference EquCab3.0 Primary Assembly

      Range
      67725555..67736364
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005602614.3 → XP_005602671.1  angiotensinogen

      See identical proteins and their annotated locations for XP_005602671.1

      UniProtKB/TrEMBL
      A0A9L0T1B5, F6W4R2
      Related
      ENSECAP00000082079.1, ENSECAT00000118634.1
      Conserved Domains (1) summary
      cl00137
      Location:97 → 470
      SERPIN; SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P01016.1 GenPept UniProtKB/Swiss-Prot:P01016

    Gene LinkOut

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