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    TXNDC5 thioredoxin domain containing 5 [ Equus caballus (horse) ]

    Gene ID: 100061945, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TXNDC5provided by VGNC
    Official Full Name
    thioredoxin domain containing 5provided by VGNC
    Primary source
    VGNC:VGNC:24681
    See related
    Ensembl:ENSECAG00000000106
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See TXNDC5 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 20 NC_009163.3 (8478954..8504251, complement)

    Chromosome 20 - NC_009163.3Genomic Context describing neighboring genes Neighboring gene microRNA mir-1291b Neighboring gene bone morphogenetic protein 6 Neighboring gene biogenesis of lysosomal organelles complex 1 subunit 5 Neighboring gene eukaryotic translation elongation factor 1 epsilon 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009163.3 Chromosome 20 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein disulfide isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein folding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    thioredoxin domain-containing protein 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009163.3 Reference EquCab3.0 Primary Assembly

      Range
      8478954..8504251 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023624432.1 → XP_023480200.1  thioredoxin domain-containing protein 5

      UniProtKB/TrEMBL
      F7CZH3
      Related
      ENSECAP00000000114.3, ENSECAT00000000158.3
      Conserved Domains (1) summary
      cd03005
      Location:190 → 290
      PDI_a_ERp46; PDIa family, endoplasmic reticulum protein 46 (ERp46) subfamily; ERp46 is an ER-resident protein containing three redox active TRX domains. Yeast complementation studies show that ERp46 can substitute for protein disulfide isomerase (PDI) function in ...
    Nucleotide Protein
    Heading Accession and Version

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