| Tie-1 has an inflammatory function in endothelial cells. | Suppression of Tie-1 in endothelial cells in vitro induces a change in the genome-wide expression profile reflecting an inflammatory function.
Chan B, Sukhatme VP., Free PMC Article | 01/21/2010 |
| the trophoblastic shell of the very early human placenta, as well as endothelial cells and ACC exhibited strong staining intensity for Tie-1 | The distribution of angiopoietin-1, angiopoietin-2 and their receptors tie-1 and tie-2 in the very early human placenta.
Seval Y, Sati L, Celik-Ozenci C, Taskin O, Demir R. | 01/21/2010 |
| Results describe the expression of angiopoietin-1, 2 and 4 and Tie-1 and 2 in gastrointestinal stromal tumors, leiomyomas and schwannomas. | Expression of angiopoietin-1, 2 and 4 and Tie-1 and 2 in gastrointestinal stromal tumor, leiomyoma and schwannoma.
Nakayama T, Inaba M, Naito S, Mihara Y, Miura S, Taba M, Yoshizaki A, Wen CY, Sekine I., Free PMC Article | 01/21/2010 |
| Activation of Tie1 ectodomain cleavage increases cartilage oligomeric protein angiopoietin 1 activation of Tie2. | Regulated proteolytic processing of Tie1 modulates ligand responsiveness of the receptor-tyrosine kinase Tie2.
Marron MB, Singh H, Tahir TA, Kavumkal J, Kim HZ, Koh GY, Brindle NP., Free PMC Article | 01/21/2010 |
| Overexpression and activation of Tie1 is associated with breast and colonic neopalsms | The receptor tyrosine kinase Tie1 is expressed and activated in epithelial tumour cell lines.
Rees KA, Singh H, Brindle NP. | 01/21/2010 |
| high expression independently associated with shorter survival in patients with early chronic phase CML | Prognostic significance of Tie-1 protein expression in patients with early chronic phase chronic myeloid leukemia.
Verstovsek S, Kantarjian H, Manshouri T, O'Brien S, Faderl S, Talpaz M, Cortes J, Albitar M. | 01/21/2010 |
| Vascular endothelial growth factor modulates the Tie-2:Tie-1 receptor complex | Vascular endothelial growth factor modulates the Tie-2:Tie-1 receptor complex.
Tsiamis AC, Morris PN, Marron MB, Brindle NP. | 01/21/2010 |