CD38 is stimulated by sequential activation of IL8 receptor, IP(3)-mediated Ca(2+) rise, and cGMP/protein kinase G and plays an essential role in IL8-induced migration of LAK cells | Activation of CD38 by interleukin-8 signaling regulates intracellular Ca2+ level and motility of lymphokine-activated killer cells. Rah SY, Park KH, Han MK, Im MJ, Kim UH. | 01/21/2010 |
Rap 1-GTP levels in platelets were reduced by NO-donors and activators of NO-sensitive soluble guanylyl cyclase | The NO/cGMP pathway inhibits Rap 1 activation in human platelets via cGMP-dependent protein kinase I. Danielewski O, Schultess J, Smolenski A. | 01/21/2010 |
Nitric oxide affects dendritic cell migration through the activation of cGMP kinase. | Nitric oxide and cGMP protein kinase (cGK) regulate dendritic-cell migration toward the lymph-node-directing chemokine CCL19. Giordano D, Magaletti DM, Clark EA., Free PMC Article | 01/21/2010 |
G-kinase regulates vasodilator-stimulated phosphoprotein activity | Vasodilator-stimulated phosphoprotein activation of serum-response element-dependent transcription occurs downstream of RhoA and is inhibited by cGMP-dependent protein kinase phosphorylation. Zhuang S, Nguyen GT, Chen Y, Gudi T, Eigenthaler M, Jarchau T, Walter U, Boss GR, Pilz RB. | 01/21/2010 |
PKG appears to be solicited for P-selectin expression when cAMP levels are elevated which suggest a cAMP/PKG-dependent pathway of platelet activation. | Differential regulation of P-selectin expression by protein kinase A and protein kinase G in thrombin-stimulated human platelets. Libersan D, Rousseau G, Merhi Y. | 01/21/2010 |
cyclic GMP-dependent protein kinase I binds to FHOD1 in vascular smooth muscle cells | Formin homology domain protein (FHOD1) is a cyclic GMP-dependent protein kinase I-binding protein and substrate in vascular smooth muscle cells. Wang Y, El-Zaru MR, Surks HK, Mendelsohn ME. | 01/21/2010 |
G-kinase I beta interacted specifically with TFII-I, an unusual transcriptional regulator that associates with multiple proteins to modulate both basal and signal-induced transcription | cGMP-dependent protein kinase I beta physically and functionally interacts with the transcriptional regulator TFII-I. Casteel DE, Zhuang S, Gudi T, Tang J, Vuica M, Desiderio S, Pilz RB. | 01/21/2010 |
cGMP-dependent protein kinase expression is regulated by Rho and Kruppel-like transcription factor-4 | Regulation of cGMP-dependent protein kinase expression by Rho and Kruppel-like transcription factor-4. Zeng Y, Zhuang S, Gloddek J, Tseng CC, Boss GR, Pilz RB. | 01/21/2010 |