| CLDN-7 is significantly overexpressed in all main histologic types of epithelial ovarian cancer | Claudin-7 expression in human epithelial ovarian cancer.
Tassi RA, Bignotti E, Falchetti M, Ravanini M, Calza S, Ravaggi A, Bandiera E, Facchetti F, Pecorelli S, Santin AD. | 01/21/2010 |
| claudin-7 and claudin-8 have potential use as immunohistochemical biomarkers in the differential diagnosis of chromophobe renal cell carcinoma and oncocytoma | Claudin-7 and claudin-8: immunohistochemical markers for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.
Osunkoya AO, Cohen C, Lawson D, Picken MM, Amin MB, Young AN. | 01/21/2010 |
| claudin-1 expression is an independent prognosticator of shortened disease-specific patient survival in clinically relevant subgroups of clear cell renal cell carcinoma | Claudin-1 protein expression is a prognostic marker of patient survival in renal cell carcinomas.
Fritzsche FR, Oelrich B, Johannsen M, Kristiansen I, Moch H, Jung K, Kristiansen G. | 01/21/2010 |
| Claudin-1 plays a crucial role in recruiting occludin to tight junctions, and occludin is involved in intercellular barrier function. | Effect of RNA interference of tight junction-related molecules on intercellular barrier function in cultured human keratinocytes.
Yamamoto T, Saeki Y, Kurasawa M, Kuroda S, Arase S, Sasaki H. | 01/21/2010 |
| Aspirin induces gastric epithelial barrier dysfunction by activating p38 MAPK via claudin-7. | Aspirin induces gastric epithelial barrier dysfunction by activating p38 MAPK via claudin-7.
Oshima T, Miwa H, Joh T. | 01/21/2010 |
| neither occludin nor claudin-7 expression was associated with clinicopathologic findings in patients with urothelial carcinoma of the upper urinary tract. | Expression of occludin and claudins 1, 3, 4, and 7 in urothelial carcinoma of the upper urinary tract.
Nakanishi K, Ogata S, Hiroi S, Tominaga S, Aida S, Kawai T. | 01/21/2010 |
| claudin-7 overexpression promotes a loss of tumor cell polarization and contributes to tumorigenesis | Defective claudin-7 regulation by Tcf-4 and Sox-9 disrupts the polarity and increases the tumorigenicity of colorectal cancer cells.
Darido C, Buchert M, Pannequin J, Bastide P, Zalzali H, Mantamadiotis T, Bourgaux JF, Garambois V, Jay P, Blache P, Joubert D, Hollande F. | 01/21/2010 |
| Claudin-3 and claudin-7 expression in effusions independently predicts poor survival in ovarian cancer. | Claudin upregulation in ovarian carcinoma effusions is associated with poor survival.
Kleinberg L, Holth A, Trope CG, Reich R, Davidson B. | 01/21/2010 |
| a reduced expression of the claudin-7 gene might lead to venous invasion and liver metastasis in colorectal cancer. | Reduced expression of the claudin-7 gene correlates with venous invasion and liver metastasis in colorectal cancer.
Oshima T, Kunisaki C, Yoshihara K, Yamada R, Yamamoto N, Sato T, Makino H, Yamagishi S, Nagano Y, Fujii S, Shiozawa M, Akaike M, Wada N, Rino Y, Masuda M, Tanaka K, Imada T. | 01/21/2010 |
| The role of extracellular loop domains of claudin-1 in determining tight junctions function, is studied. | A key claudin extracellular loop domain is critical for epithelial barrier integrity.
Mrsny RJ, Brown GT, Gerner-Smidt K, Buret AG, Meddings JB, Quan C, Koval M, Nusrat A., Free PMC Article | 01/21/2010 |
| Reduced claudin-7 expression correlates with loss of differentiation in thyroid neoplasms. | Tight junctions in thyroid carcinogenesis: diverse expression of claudin-1, claudin-4, claudin-7 and occludin in thyroid neoplasms.
Tzelepi VN, Tsamandas AC, Vlotinou HD, Vagianos CE, Scopa CD. | 01/21/2010 |
| Claudin-7 to be a candidate expression marker for distinguishing chromophobe renal cell carcinoma from other renal tumor subtypes, including the morphologically similar oncocytoma. | Claudin-7 immunohistochemistry in renal tumors: a candidate marker for chromophobe renal cell carcinoma identified by gene expression profiling.
Hornsby CD, Cohen C, Amin MB, Picken MM, Lawson D, Yin-Goen Q, Young AN. | 01/21/2010 |
| When compared, adenocarcinomas and squamous cell carcinomas revealed significant differences in CLDN7 expression. | Distinct claudin expression profile in histologic subtypes of lung cancer.
Moldvay J, Jäckel M, Páska C, Soltész I, Schaff Z, Kiss A. | 01/21/2010 |
| Results show show that claudin 7 expression changed with the gastric carcinogenic process and that this is implicated in cancer characteristics. | Up-regulated claudin 7 expression in intestinal-type gastric carcinoma.
Park JY, Park KH, Oh TY, Hong SP, Jeon TJ, Kim CH, Park SW, Chung JB, Song SY, Bang S. | 01/21/2010 |
| Claudin tight junction proteins in endoscopy biopsy samples showed Barrett's metaplasia contains more claudin-2 and claudin-3 than found in normal esophageal mucosa, but markedly lower claudins 1 and 5, indicating very different tight junction barriers. | Transepithelial leak in Barrett's esophagus.
Mullin JM, Valenzano MC, Trembeth S, Allegretti PD, Verrecchio JJ, Schmidt JD, Jain V, Meddings JB, Mercogliano G, Thornton JJ. | 01/21/2010 |
| induction of claudin7 expression by ELF3 appears critical to the formation of the epithelial structures in biphasic synovial sarcoma | Expression of claudin7 is tightly associated with epithelial structures in synovial sarcomas and regulated by an Ets family transcription factor, ELF3.
Kohno Y, Okamoto T, Ishibe T, Nagayama S, Shima Y, Nishijo K, Shibata KR, Fukiage K, Otsuka S, Uejima D, Araki N, Naka N, Nakashima Y, Aoyama T, Nakayama T, Nakamura T, Toguchida J. | 01/21/2010 |
| Loss of claudin-1 expression proved to be a strong predictor of disease recurrence and poor patient survival in stage II colon cancer. | Claudin-1 is a strong prognostic indicator in stage II colonic cancer: a tissue microarray study.
Resnick MB, Konkin T, Routhier J, Sabo E, Pricolo VE. | 01/21/2010 |
| Claudin-1 and claudin-7 may play a significant role in tumor progression of cervical neoplasia and may represent useful markers for malignant transformation of cervical squamous cells. | Increased expressions of claudin-1 and claudin-7 during the progression of cervical neoplasia.
Lee JW, Lee SJ, Seo J, Song SY, Ahn G, Park CS, Lee JH, Kim BG, Bae DS. | 01/21/2010 |
| claudin-7-associated EpCAM is recruited into (tetraspanin-enriched membrane microdomains) and forms a complex with CO-029 and CD44v6 that facilitates metastasis formation | A complex of EpCAM, claudin-7, CD44 variant isoforms, and tetraspanins promotes colorectal cancer progression.
Kuhn S, Koch M, Nübel T, Ladwein M, Antolovic D, Klingbeil P, Hildebrand D, Moldenhauer G, Langbein L, Franke WW, Weitz J, Zöller M. | 01/21/2010 |
| Loss of claudin-7 correlates with histological grade in both ductal carcinoma in situ and invasive ductal carcinoma of the breast, providing insight into the potential role of CLDN-7 in the progression and ability of breast cancer cells to disseminate. | Loss of the tight junction protein claudin-7 correlates with histological grade in both ductal carcinoma in situ and invasive ductal carcinoma of the breast.
Kominsky SL, Argani P, Korz D, Evron E, Raman V, Garrett E, Rein A, Sauter G, Kallioniemi OP, Sukumar S. | 01/21/2010 |
| 2 forms of claudin-7, a full-length form with 211 AA residues and a C-terminal truncated form with 158 AA residues, are able to regulate the expression of a tissue-specific protein, prostate-specific antigen, in the LNCaP prostate cancer cell line. | Regulation of the expression of the prostate-specific antigen by claudin-7.
Zheng JY, Yu D, Foroohar M, Ko E, Chan J, Kim N, Chiu R, Pang S. | 01/21/2010 |
| Overexpression of claudin-7 is associated with gastric tumorigenesis | Expression of tight-junction protein claudin-7 is an early event in gastric tumorigenesis.
Johnson AH, Frierson HF, Zaika A, Powell SM, Roche J, Crowe S, Moskaluk CA, El-Rifai W., Free PMC Article | 01/21/2010 |