U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    Tlr9 toll-like receptor 9 [ Mus musculus (house mouse) ]

    Gene ID: 81897, updated on 15-Jul-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Toll-like receptor 9 (TLR9) gene deletion-mediated fracture healing in type II diabetic osteoporosis associates with inhibition of the nuclear factor-kappa B (NF-kappaB) signaling pathway.

    Toll-like receptor 9 (TLR9) gene deletion-mediated fracture healing in type II diabetic osteoporosis associates with inhibition of the nuclear factor-kappa B (NF-κB) signaling pathway.
    Han J, Zheng Q, Cheng Y, Liu Y, Bai Y, Yan B, Guo S, Yu J, Li X, Wang C., Free PMC Article

    06/25/2022
    Neurotropic EV71 causes encephalitis by engaging intracellular TLR9 to elicit neurotoxic IL12-p40-iNOS signaling.

    Neurotropic EV71 causes encephalitis by engaging intracellular TLR9 to elicit neurotoxic IL12-p40-iNOS signaling.
    Lai RH, Chow YH, Chung NH, Chen TC, Shie FS, Juang JL., Free PMC Article

    04/23/2022
    Identification of Potential Biomarkers of Type 2 Diabetes Mellitus-Related Immune Infiltration Using Weighted Gene Coexpression Network Analysis.

    Identification of Potential Biomarkers of Type 2 Diabetes Mellitus-Related Immune Infiltration Using Weighted Gene Coexpression Network Analysis.
    Zhou J, Zhang X, Ji L, Jiang G., Free PMC Article

    04/2/2022
    Mitochondrial DNA and TLR9 activation contribute to SARS-CoV-2-induced endothelial cell damage.

    Mitochondrial DNA and TLR9 activation contribute to SARS-CoV-2-induced endothelial cell damage.
    Costa TJ, Potje SR, Fraga-Silva TFC, da Silva-Neto JA, Barros PR, Rodrigues D, Machado MR, Martins RB, Santos-Eichler RA, Benatti MN, de Sá KSG, Almado CEL, Castro ÍA, Pontelli MC, Serra L, Carneiro FS, Becari C, Louzada-Junior P, Oliveira RDR, Zamboni DS, Arruda E, Auxiliadora-Martins M, Giachini FRC, Bonato VLD, Zachara NE, Bomfim GF, Tostes RC., Free PMC Article

    03/5/2022
    IRF8 Impacts Self-Renewal of Hematopoietic Stem Cells by Regulating TLR9 Signaling Pathway of Innate Immune Cells.

    IRF8 Impacts Self-Renewal of Hematopoietic Stem Cells by Regulating TLR9 Signaling Pathway of Innate Immune Cells.
    Li D, Zhang Y, Qiu Q, Wang J, Zhao X, Jiao B, Zhang X, Yu S, Xu P, Dan Y, Xiao X, Wang P, Liu M, Xia Z, Huang Z, Zhang R, Li J, Xie X, Zhang Y, Liu C, Liu P, Ren R., Free PMC Article

    02/12/2022
    TLR9 signalling inhibits Plasmodium liver infection by macrophage activation.

    TLR9 signalling inhibits Plasmodium liver infection by macrophage activation.
    Kordes M, Ormond L, Rausch S, Matuschewski K, Hafalla JCR.

    02/12/2022
    The Protective Role of TLR2 Mediates Impaired Autophagic Flux by Activating the mTOR Pathway During Neospora caninum Infection in Mice.

    The Protective Role of TLR2 Mediates Impaired Autophagic Flux by Activating the mTOR Pathway During Neospora caninum Infection in Mice.
    Wang J, Wang X, Gong P, Ren F, Li X, Zhang N, Zhang X, Zhang X, Li J., Free PMC Article

    02/5/2022
    Matrix lumican endocytosed by immune cells controls receptor ligand trafficking to promote TLR4 and restrict TLR9 in sepsis.

    Matrix lumican endocytosed by immune cells controls receptor ligand trafficking to promote TLR4 and restrict TLR9 in sepsis.
    Maiti G, Frikeche J, Lam CY, Biswas A, Shinde V, Samanovic M, Kagan JC, Mulligan MJ, Chakravarti S., Free PMC Article

    12/4/2021
    Toll-like Receptor 9 Agonists as Adjuvants for Nanoparticle-Based Nicotine Vaccine.

    Toll-like Receptor 9 Agonists as Adjuvants for Nanoparticle-Based Nicotine Vaccine.
    Hu Y, Smith D, Frazier E, Zhao Z, Zhang C.

    11/6/2021
    TLR4 deficiency upregulates TLR9 expression and enhances irinotecan-related intestinal mucositis and late-onset diarrhoea.

    TLR4 deficiency upregulates TLR9 expression and enhances irinotecan-related intestinal mucositis and late-onset diarrhoea.
    Wong DVT, Holanda RBF, Cajado AG, Bandeira AM, Pereira JFB, Amorim JO, Torres CS, Ferreira LMM, Lopes MHS, Oliveira RTG, Pereira AF, Sant'Ana RO, Arruda LM, Ribeiro-Júnior HL, Pinheiro RF, Almeida PRC, Carvalho RF, Chaves FF, Rocha-Filho DR, Cunha FQ, Lima-Júnior RCP.

    10/30/2021
    Construction of Monomeric and Dimeric G-Quadruplex-Structured CpG Oligodeoxynucleotides for Enhanced Uptake and Activation in TLR9-Positive Macrophages.

    Construction of Monomeric and Dimeric G-Quadruplex-Structured CpG Oligodeoxynucleotides for Enhanced Uptake and Activation in TLR9-Positive Macrophages.
    Liao W, Tan M, Kusamori K, Takakura Y, Nishikawa M.

    10/23/2021
    The impact of cell maturation and tissue microenvironments on the expression of endosomal Toll-like receptors in monocytes and macrophages.

    The impact of cell maturation and tissue microenvironments on the expression of endosomal Toll-like receptors in monocytes and macrophages.
    Sato R, Reuter T, Hiranuma R, Shibata T, Fukui R, Motoi Y, Murakami Y, Tsukamoto H, Yamazaki S, Liu K, Saitoh SI, Latz E, Miyake K.

    10/2/2021
    Toll-Like Receptor 9 Is Involved in NLRP3 Inflammasome Activation and IL-1beta Production Through Monosodium Urate-Induced Mitochondrial DNA.

    Toll-Like Receptor 9 Is Involved in NLRP3 Inflammasome Activation and IL-1β Production Through Monosodium Urate-Induced Mitochondrial DNA.
    Kim SK, Park KY, Choe JY.

    09/25/2021
    Inhibition of the TLR9-dependent p38 MAPK signaling pathway improves the pathogenesis of primary Sjogren's syndrome in the NOD/Ltj mouse.

    Inhibition of the TLR9-dependent p38 MAPK signaling pathway improves the pathogenesis of primary Sjögren's syndrome in the NOD/Ltj mouse.
    Cao N, Shi H, Chen C, Zheng L, Yu C.

    09/4/2021
    Selective nanoparticle-mediated targeting of renal tubular Toll-like receptor 9 attenuates ischemic acute kidney injury.

    Selective nanoparticle-mediated targeting of renal tubular Toll-like receptor 9 attenuates ischemic acute kidney injury.
    Han SJ, Williams RM, D'Agati V, Jaimes EA, Heller DA, Lee HT., Free PMC Article

    08/28/2021
    The role of Toll-like receptor 9 in a murine model of Cryptococcus gattii infection.

    The role of Toll-like receptor 9 in a murine model of Cryptococcus gattii infection.
    da Silva-Junior EB, Firmino-Cruz L, Guimarães-de-Oliveira JC, De-Medeiros JVR, de Oliveira Nascimento D, Freire-de-Lima M, de Brito-Gitirana L, Morrot A, Previato JO, Mendonça-Previato L, Decote-Ricardo D, de Matos Guedes HL, Freire-de-Lima CG., Free PMC Article

    08/14/2021
    Intratumoral immunotherapy with anti-PD-1 and TLR9 agonist induces systemic antitumor immunity without accelerating rejection of cardiac allografts.

    Intratumoral immunotherapy with anti-PD-1 and TLR9 agonist induces systemic antitumor immunity without accelerating rejection of cardiac allografts.
    Dang N, Waer M, Sprangers B, Lin Y.

    08/7/2021
    Mitochondrial DNA from hepatocytes induces upregulation of interleukin-33 expression of macrophages in nonalcoholic steatohepatitis.

    Mitochondrial DNA from hepatocytes induces upregulation of interleukin-33 expression of macrophages in nonalcoholic steatohepatitis.
    Gao Y, Wang Y, Liu H, Liu Z, Zhao J.

    07/24/2021
    HSV-1/TLR9-Mediated IFNbeta and TNFalpha Induction Is Mal-Dependent in Macrophages.

    HSV-1/TLR9-Mediated IFNβ and TNFα Induction Is Mal-Dependent in Macrophages.
    Zyzak J, Mitkiewicz M, Leszczyńska E, Reniewicz P, Moynagh PN, Siednienko J., Free PMC Article

    07/17/2021
    TLR9 activation induces aberrant IgA glycosylation via APRIL- and IL-6-mediated pathways in IgA nephropathy.

    TLR9 activation induces aberrant IgA glycosylation via APRIL- and IL-6-mediated pathways in IgA nephropathy.
    Makita Y, Suzuki H, Kano T, Takahata A, Julian BA, Novak J, Suzuki Y., Free PMC Article

    07/10/2021
    TLR9 deficiency alleviates doxorubicin-induced cardiotoxicity via the regulation of autophagy.

    TLR9 deficiency alleviates doxorubicin-induced cardiotoxicity via the regulation of autophagy.
    Guo Z, Tang N, Liu FY, Yang Z, Ma SQ, An P, Wu HM, Fan D, Tang QZ., Free PMC Article

    06/5/2021
    Induction of antitumor immunity in mice by the combination of nanoparticle-based photothermolysis and anti-PD-1 checkpoint inhibition.

    Induction of antitumor immunity in mice by the combination of nanoparticle-based photothermolysis and anti-PD-1 checkpoint inhibition.
    Cao Q, Wang W, Zhou M, Huang Q, Wen X, Zhao J, Shi S, Geng K, Li F, Hatakeyama H, Xu C, Piwnica-Worms D, Peng W, Zhou D, Sood AK, Li C., Free PMC Article

    05/29/2021
    Macrophage-Specific Toll Like Receptor 9 (TLR9) Causes Corpus Cavernosum Dysfunction in Mice Fed a High Fat Diet.

    Macrophage-Specific Toll Like Receptor 9 (TLR9) Causes Corpus Cavernosum Dysfunction in Mice Fed a High Fat Diet.
    Priviero F, Calmasini F, Dela Justina V, Wenceslau CF, McCarthy CG, Webb RC., Free PMC Article

    05/22/2021
    TLR9 Deficiency in B Cells Promotes Immune Tolerance via Interleukin-10 in a Type 1 Diabetes Mouse Model.

    TLR9 Deficiency in B Cells Promotes Immune Tolerance via Interleukin-10 in a Type 1 Diabetes Mouse Model.
    Sha S, Pearson JA, Peng J, Hu Y, Huang J, Xing Y, Zhang L, Zhu Y, Zhao H, Wong FS, Chen L, Wen L., Free PMC Article

    05/15/2021
    MAIR-II deficiency ameliorates cardiac remodelling post-myocardial infarction by suppressing TLR9-mediated macrophage activation.

    MAIR-II deficiency ameliorates cardiac remodelling post-myocardial infarction by suppressing TLR9-mediated macrophage activation.
    Yonebayashi S, Tajiri K, Murakoshi N, Xu D, Li S, Feng D, Okabe Y, Yuan Z, Song Z, Aonuma K, Shibuya A, Aonuma K, Ieda M., Free PMC Article

    05/15/2021