Genomic determinants implicated in the glucocorticoid-mediated induction of KLF9 in pulmonary epithelial cells. | Genomic determinants implicated in the glucocorticoid-mediated induction of KLF9 in pulmonary epithelial cells. Mostafa MM, Bansal A, Michi AN, Sasse SK, Proud D, Gerber AN, Newton R., Free PMC Article | 09/18/2021 |
KLF9 regulates PRDX6 expression in hyperglycemia-aggravated bupivacaine neurotoxicity. | KLF9 regulates PRDX6 expression in hyperglycemia-aggravated bupivacaine neurotoxicity. Li H, Weng Y, Lai L, Lei H, Xu S, Zhang Y, Li L. | 07/31/2021 |
MiR-142-3p inhibits adipogenic differentiation and autophagy in obesity through targeting KLF9. | MiR-142-3p inhibits adipogenic differentiation and autophagy in obesity through targeting KLF9. Wei Z, Qin X, Kang X, Zhou H, Wang S, Wei D. | 07/3/2021 |
LncRNA SNHG15 promotes the proliferation of nasopharyngeal carcinoma via sponging miR-141-3p to upregulate KLF9. | LncRNA SNHG15 promotes the proliferation of nasopharyngeal carcinoma via sponging miR-141-3p to upregulate KLF9. Yi TW, Lv XX, Fan H, Zan N, Su XD. | 04/17/2021 |
MiRNA-20a-5p accelerates the proliferation and invasion of non-small cell lung cancer by targeting and downregulating KLF9. | MiRNA-20a-5p accelerates the proliferation and invasion of non-small cell lung cancer by targeting and downregulating KLF9. Fang QY, Deng QF, Luo J, Zhou CC. | 03/20/2021 |
The miR-140-5p/KLF9/KCNQ1 axis promotes the progression of renal cell carcinoma. | The miR-140-5p/KLF9/KCNQ1 axis promotes the progression of renal cell carcinoma. Huang C, Li J, Zhang X, Xiong T, Ye J, Yu J, Gui Y. | 03/6/2021 |
MiR-141 promotes cell proliferation and invasion in non-small cell lung cancer by targeting KLF9. | MiR-141 promotes cell proliferation and invasion in non-small cell lung cancer by targeting KLF9. Kong YJ, Tan XX, Zhang Y, He QJ, Zhao L, Meng Q. | 10/24/2020 |
CircPTPRA acts as a tumor suppressor in bladder cancer by sponging miR-636 and upregulating KLF9. | CircPTPRA acts as a tumor suppressor in bladder cancer by sponging miR-636 and upregulating KLF9. He Q, Huang L, Yan D, Bi J, Yang M, Huang J, Lin T., Free PMC Article | 10/24/2020 |
Dexamethasone induces aberrant macrophage immune function and apoptosis. | Dexamethasone induces aberrant macrophage immune function and apoptosis. Ai F, Zhao G, Lv W, Liu B, Lin J., Free PMC Article | 08/22/2020 |
Among the GC cell lines, KLF9 was low in MKN45 and BGC-823 cells, but high in SGC-7901 and HGC-27 cells. Ectopic expression of KLF9 evidently inhibited the migration and invasion capabilities of GC cells. Conversely, knockdown of KLF9 endowed GC cells with stronger invasive capacity. KLF9 significantly suppresses GC cell invasion and metastasis through inhibiting MMP28 transcription. | KLF9 suppresses gastric cancer cell invasion and metastasis through transcriptional inhibition of MMP28. Li Y, Sun Q, Jiang M, Li S, Zhang J, Xu Z, Guo D, Gu T, Wang B, Xiao L, Zhou T, Zhuo W. | 05/30/2020 |
Decreased KLF9 expression is associated with neuroblastoma. | Krüppel-like factor 9 promotes neuroblastoma differentiation via targeting the sonic hedgehog signaling pathway. Chen S, Gu S, Xu M, Mei D, Xiao Y, Chen K, Yan Z. | 05/9/2020 |
miR-142-3p directly targeted KLF9, regulated VEGFA expression, and was protective against the growth of ectopic endometriotic lesions. | MicroRNA-142-3p suppresses endometriosis by regulating KLF9-mediated autophagy in vitro and in vivo. Ma L, Li Z, Li W, Ai J, Chen X., Free PMC Article | 05/2/2020 |
XBP1s transcriptionally activates KLF9 under conditions of high ER stress. | XBP1-KLF9 Axis Acts as a Molecular Rheostat to Control the Transition from Adaptive to Cytotoxic Unfolded Protein Response. Fink EE, Moparthy S, Bagati A, Bianchi-Smiraglia A, Lipchick BC, Wolff DW, Roll MV, Wang J, Liu S, Bakin AV, Kandel ES, Lee AH, Nikiforov MA., Free PMC Article | 01/11/2020 |
Our current study suggests that miR-660-5p may control Non-small cell lung cancer (NSCLC) proliferation, viability, and metastasis by targeting KLF9, which provides a potential therapeutic target for NSCLC. | Exosomal miR-660-5p promotes tumor growth and metastasis in non-small cell lung cancer. Qi Y, Zha W, Zhang W. | 12/28/2019 |
KLF9 levels decrease during melanoma progression.BRAF-V600 upregulates KLF9 and requires KLF9-dependent reactive oxygen species cell proliferation in human melanocytes. | KLF9-dependent ROS regulate melanoma progression in stage-specific manner. Bagati A, Moparthy S, Fink EE, Bianchi-Smiraglia A, Yun DH, Kolesnikova M, Udartseva OO, Wolff DW, Roll MV, Lipchick BC, Han Z, Kozlova NI, Jowdy P, Berman AE, Box NF, Rodriguez C, Bshara W, Kandel ES, Soengas MS, Paragh G, Nikiforov MA., Free PMC Article | 10/26/2019 |
Low KLF9 expression is associated with proliferation and invasion of glioma. | MicroRNA‑940 promotes cell proliferation and invasion of glioma by directly targeting Kruppel‑like factor 9. Zhang D, Hao P, Jin L, Wang Y, Yan Z, Wu S. | 06/1/2019 |
MiR-889 may play a potential therapeutic role for NSCLC by targeting KLF9 to control NSCLC proliferation and migration. | MiR-889 promotes cell growth in human non-small cell lung cancer by regulating KLF9. Han X, Tang Y, Dai Y, Hu S, Zhou J, Liu X, Zhu J, Wu Y. | 04/20/2019 |
KLF1 and KLF9 synergistically regulated erythroid differentiation through the PI3K-Akt and FoxO signaling pathways. | [Synergistic regulation of the erythroid differentiation of K562 cells by KLF1 and KLF9]. Ren L, Xiao RD, Zhang Q, Lou XM, Zhang ZJ, Fang XD. | 03/30/2019 |
THBS4 had positive effects on gastric cancer cell proliferation, progression, and metastasis via targeting KLF9. | THBS4 predicts poor outcomes and promotes proliferation and metastasis in gastric cancer. Chen X, Huang Y, Wang Y, Wu Q, Hong S, Huang Z. | 03/30/2019 |
KLF9 and BCL3 as transcription factors that enhance reprogramming of primordial germ cells | Identification of KLF9 and BCL3 as transcription factors that enhance reprogramming of primordial germ cells. Otsuka K, Takehara A, Chiba N, Matsui Y., Free PMC Article | 03/23/2019 |
Study results revealed that in both, tissue samples and pancreatic cancer cell lines, KLF9 exhibited relatively lower expression. In addition, low KLF9 expression was related to the differentiation and depth of vascular invasion and was associated with a poor overall survival rate. | Expression of KLF9 in pancreatic cancer and its effects on the invasion, migration, apoptosis, cell cycle distribution, and proliferation of pancreatic cancer cell lines. Zhong Z, Zhou F, Wang D, Wu M, Zhou W, Zou Y, Li J, Wu L, Yin X. | 01/12/2019 |
results demonstrated the molecular interaction between miR-378 and KLF9, indicating the therapeutic potential of miR-378 for osteosarcoma. | MiR-378 promotes the cell proliferation of osteosarcoma through down-regulating the expression of Kruppel-like factor 9. Peng N, Miao Z, Wang L, Liu B, Wang G, Guo X. | 12/1/2018 |
KLF9 suppressed tumorigenicity of the pancreatic ductal adenocarcinoma by negatively regulating frizzled-5. | Krüppel-like factor 9 suppressed tumorigenicity of the pancreatic ductal adenocarcinoma by negatively regulating frizzled-5. Ji P, Fan X, Ma X, Wang X, Zhang J, Mao Z. | 10/13/2018 |
KLF9 could down-regulate MMP9 expression to inhibit breast cancer metastasis. | Krüppel-like factor 9 down-regulates matrix metalloproteinase 9 transcription and suppresses human breast cancer invasion. Bai XY, Li S, Wang M, Li X, Yang Y, Xu Z, Li B, Li Y, Xia K, Chen H, Wu H. | 12/9/2017 |
KLF9 status was associated with differentiation and vascular invasion expression and was found to be a valuable prognostic factor for patients with pancreatic ductal adenocarcinoma | KLF9 Is a Prognostic Indicator in Human Pancreatic Ductal Adenocarcinoma. Mao Z, Fan X, Zhang J, Wang X, Ma X, Michalski CW, Zhang Y. | 09/2/2017 |