involucrin gene expression inhibition by apigenin is associated with a specific reduction in phosphorylation of protein kinase Cdelta Tyr311 | Apigenin inhibition of involucrin gene expression is associated with a specific reduction in phosphorylation of protein kinase Cdelta Tyr311. Balasubramanian S, Zhu L, Eckert RL. | 01/21/2010 |
transactivation of involucrin by lens epithelium-derived growth factor (LEDGF) | Transactivation of involucrin, a marker of differentiation in keratinocytes, by lens epithelium-derived growth factor (LEDGF). Kubo E, Fatma N, Sharma P, Shinohara T, Chylack LT Jr, Akagi Y, Singh DP. | 01/21/2010 |
Involucrin expression of keratinocytes is suppressed by roxithromycin through direct inhibition of AP-1 and indirect inhibition of NF-kappaB. | Roxithromycin suppresses involucrin expression by modulation of activator protein-1 and nuclear factor-kappaB activities of keratinocytes. Takahashi H, Hashimoto Y, Ishida-Yamamoto A, Iizuka H. | 01/21/2010 |
the AP-1 site and the vitamin D response element in the involucrin promoter play important roles in mediating the action of 1,25-dihydroxyvitamin D3 on involucrin expression | The vitamin D response element of the involucrin gene mediates its regulation by 1,25-dihydroxyvitamin D3. Bikle DD, Ng D, Oda Y, Hanley K, Feingold K, Xie Z. | 01/21/2010 |
p38 delta is the major p38 isoform driving suprabasal hINV gene expression | A regulatory role for p38 delta MAPK in keratinocyte differentiation. Evidence for p38 delta-ERK1/2 complex formation. Efimova T, Broome AM, Eckert RL. | 01/21/2010 |
AP1, Sp1, and C/EBP transcription factors are required for appropriate differentiation-dependent involucrin expression. | The distal and proximal regulatory regions of the involucrin gene promoter have distinct functions and are required for in vivo involucrin expression. Crish JF, Gopalakrishnan R, Bone F, Gilliam AC, Eckert RL. | 01/21/2010 |
human involucrin promoter activity is regulated by green tea polyphenol and curcumin via opposing effects on CCAAT/enhancer-binding protein function | Green tea polyphenol and curcumin inversely regulate human involucrin promoter activity via opposing effects on CCAAT/enhancer-binding protein function. Balasubramanian S, Eckert RL. | 01/21/2010 |
Transcriptional activation of the involucrin gene by calcium in keratinocytes. | Regulation of involucrin gene expression by calcium in normal human keratinocytes. Ng DC, Su MJ, Kim R, Bikle DD. | 01/21/2010 |
Pyk2 regulation is associated with increased expression of Fra-1 and JunD, activator protein-1 transcription factors known to be required for involucrin expression. | The role of proline-rich protein tyrosine kinase 2 in differentiation-dependent signaling in human epidermal keratinocytes. Schindler EM, Baumgartner M, Gribben EM, Li L, Efimova T. | 01/21/2010 |
There is a major role for STAT5a in the differentiation of keratinocytes, where it contributes to involucrin expression by activating the PPARgamma signal. | STAT5a/PPARgamma pathway regulates involucrin expression in keratinocyte differentiation. Dai X, Sayama K, Shirakata Y, Hanakawa Y, Yamasaki K, Tokumaru S, Yang L, Wang X, Hirakawa S, Tohyama M, Yamauchi T, Takashi K, Kagechika H, Hashimoto K. | 01/21/2010 |
involucrin gene contains distinct regulatory elements that regulate expression during epidermal differentiation | The human involucrin gene contains spatially distinct regulatory elements that regulate expression during early versus late epidermal differentiation. Crish JF, Bone F, Banks EB, Eckert RL. | 01/21/2010 |