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    GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 [ Homo sapiens (human) ]

    Gene ID: 2982, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    A novel insight into the heme and NO/CO binding mechanism of the alpha subunit of human soluble guanylate cyclase

    A novel insight into the heme and NO/CO binding mechanism of the alpha subunit of human soluble guanylate cyclase.
    Zhong F, Pan J, Liu X, Wang H, Ying T, Su J, Huang ZX, Tan X.

    03/24/2012
    C-alpha1 sGC splice form is expressed at high levels in differentiating cells and its intracellular distribution varies from canonical alpha1 sGC subunit.

    Nitric oxide receptor soluble guanylyl cyclase undergoes splicing regulation in differentiating human embryonic cells.
    Sharin VG, Mujoo K, Kots AY, Martin E, Murad F, Sharina IG., Free PMC Article

    10/22/2011
    NO, depending on its concentration, may act in human PBMCs as a stimulator of IL-6 expression and modulator of NF-KB involving the sGC/cGMP/PKG pathway

    Nitric oxide affects IL-6 expression in human peripheral blood mononuclear cells involving cGMP-dependent modulation of NF-κB activity.
    Siednienko J, Nowak J, Moynagh PN, Gorczyca WA.

    09/10/2011
    guanylate cyclase has a role in pulmonary arterial hypertension

    Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension.
    Schermuly RT, Stasch JP, Pullamsetti SS, Middendorff R, Müller D, Schlüter KD, Dingendorf A, Hackemack S, Kolosionek E, Kaulen C, Dumitrascu R, Weissmann N, Mittendorf J, Klepetko W, Seeger W, Ghofrani HA, Grimminger F.

    01/21/2010
    Soluble guanylate cyclases could be the target molecules for controlling neo-vascularization in a subset of human malignant gliomas.

    Inhibition of angiogenesis in human glioma cell lines by antisense RNA from the soluble guanylate cyclase genes, GUCY1A3 and GUCY1B3.
    Saino M, Maruyama T, Sekiya T, Kayama T, Murakami Y.

    01/21/2010
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