| a direct link between GSK-3beta and MLK3 activation in a neuronal cell death pathway and identify MLK3 as a direct downstream target of GSK-3beta. | Glycogen synthase kinase-3beta induces neuronal cell death via direct phosphorylation of mixed lineage kinase 3.
Mishra R, Barthwal MK, Sondarva G, Rana B, Wong L, Chatterjee M, Woodgett JR, Rana A., Free PMC Article | 01/21/2010 |
| These data raise the possibility that CRISP2 is a MAP3K11-modifying protein or, alternatively, that MAP3K11 acts to phosphorylate CRISP2 during acrosome development. | Cysteine-rich secretory protein 2 binds to mitogen-activated protein kinase kinase kinase 11 in mouse sperm.
Gibbs GM, Bianco DM, Jamsai D, Herlihy A, Ristevski S, Aitken RJ, Kretser DM, O'Bryan MK. | 01/21/2010 |
| MLK3 contributes to the TNF signaling pathway that activates JNK. | Role of MLK3 in the regulation of mitogen-activated protein kinase signaling cascades.
Brancho D, Ventura JJ, Jaeschke A, Doran B, Flavell RA, Davis RJ., Free PMC Article | 01/21/2010 |
| MLK3 is involved in C-EBP beta regulated, IFN-gamma signaling | A role for mixed lineage kinases in regulating transcription factor CCAAT/enhancer-binding protein-{beta}-dependent gene expression in response to interferon-{gamma}.
Roy SK, Shuman JD, Platanias LC, Shapiro PS, Reddy SP, Johnson PF, Kalvakolanu DV. | 01/21/2010 |