| These results suggest that tricellulin is stably expressed in human nasal epithelial cells and may play an important role for the sealing of the corner at tricellular contacts to prevent infiltration by various inhaled viruses and antigens. | Expression and localization of tricellulin in human nasal epithelial cells in vivo and in vitro.
Ohkuni T, Kojima T, Ogasawara N, Masaki T, Ninomiya T, Kikuchi S, Go M, Takano K, Himi T, Sawada N. | 03/15/2010 |
| TRiC does not physically block the polyQ tract of Htt itself, but rather sequesters a short Htt sequence element, N-terminal to the polyQ tract, that promotes the amyloidogenic conformation. | The chaperonin TRiC blocks a huntingtin sequence element that promotes the conformational switch to aggregation.
Tam S, Spiess C, Auyeung W, Joachimiak L, Chen B, Poirier MA, Frydman J., Free PMC Article | 01/21/2010 |
| Data suggest that at low tricellulin expression the tricellular tight junction central tube forms a pathway, but at higher expression tricellulin forms a barrier for macromolecules in tricellular TJs and in bicellular TJs for solutes of all sizes. | Tricellulin forms a barrier to macromolecules in tricellular tight junctions without affecting ion permeability.
Krug SM, Amasheh S, Richter JF, Milatz S, Günzel D, Westphal JK, Huber O, Schulzke JD, Fromm M., Free PMC Article | 01/21/2010 |
| Differential phosphorylation of tricellulin by casein kinase 1 (CK1) and casein kinase 2 | Differential phosphorylation of occludin and tricellulin by CK2 and CK1.
Dörfel MJ, Westphal JK, Huber O. | 01/21/2010 |
| Splice-site mutations in the TRIC gene underlie autosomal recessive nonsyndromic hearing impairment | Splice-site mutations in the TRIC gene underlie autosomal recessive nonsyndromic hearing impairment in Pakistani families.
Chishti MS, Bhatti A, Tamim S, Lee K, McDonald ML, Leal SM, Ahmad W., Free PMC Article | 01/21/2010 |
| Maps to 5q12.3-q14.1. | A new locus for nonsyndromic deafness DFNB49 maps to chromosome 5q12.3-q14.1.
Ramzan K, Shaikh RS, Ahmad J, Khan SN, Riazuddin S, Ahmed ZM, Friedman TB, Wilcox ER, Riazuddin S. | 01/21/2010 |