| rFN/CDHs may induce hMSCs differentiation into osteoblasts and PLGA/collagen nanofibers loaded with rFN/CDHs have potential in bone tissue engineering. | Core-shell PLGA/collagen nanofibers loaded with recombinant FN/CDHs as bone tissue engineering scaffolds.
Wang J, Cui X, Zhou Y, Xiang Q. | 02/21/2015 |
| Cadherin-11 regulates the expression of TGF-B1 and affects smooth muscle cell differentiation through a pathway that was dependent on TGF-B receptor II. | Cadherin-11 regulates both mesenchymal stem cell differentiation into smooth muscle cells and the development of contractile function in vivo.
Alimperti S, You H, George T, Agarwal SK, Andreadis ST., Free PMC Article | 01/31/2015 |
| Cadherin-11 may play a role in renal cell carcinoma bone metastasis. | Cadherin-11 in renal cell carcinoma bone metastasis.
Satcher RL, Pan T, Cheng CJ, Lee YC, Lin SC, Yu G, Li X, Hoang AG, Tamboli P, Jonasch E, Gallick GE, Lin SH., Free PMC Article | 01/24/2015 |
| Data indicate that Cadherin-11 (CDH11) is increased in cells during normal cerebral cortical development. | Cadherin-11 regulates motility in normal cortical neural precursors and glioblastoma.
Schulte JD, Srikanth M, Das S, Zhang J, Lathia JD, Yin L, Rich JN, Olson EC, Kessler JA, Chenn A., Free PMC Article | 08/23/2014 |
| We also demonstrated that CDH11 acts as an inhibitor of tumour growth, motility and dissemination. | Epigenetic disruption of cadherin-11 in human cancer metastasis.
Carmona FJ, Villanueva A, Vidal A, Muñoz C, Puertas S, Penin RM, Gomà M, Lujambio A, Piulats JM, Mesía R, Sánchez-Céspedes M, Manós M, Condom E, Eccles SA, Esteller M., Free PMC Article | 12/8/2012 |
| CDH11-deficient mice had decreased fibrotic endpoints in the bleomycin model of pulmonary fibrosis compared to wild-type mice. | Cadherin-11 contributes to pulmonary fibrosis: potential role in TGF-β production and epithelial to mesenchymal transition.
Schneider DJ, Wu M, Le TT, Cho SH, Brenner MB, Blackburn MR, Agarwal SK., Free PMC Article | 04/14/2012 |
| The pattern of haplotype diversity across the quantitative trait loci (QTL) region and expression profiles of QTL genes suggested that of the 12, cadherin 11 (Cdh11) was most likely the causal gene. | Identification of quantitative trait loci influencing skeletal architecture in mice: emergence of Cdh11 as a primary candidate gene regulating femoral morphology.
Farber CR, Kelly SA, Baruch E, Yu D, Hua K, Nehrenberg DL, de Villena FP, Buus RJ, Garland T Jr, Pomp D., Free PMC Article | 12/17/2011 |
| cad-11 modulates synovial fibroblasts to evoke inflammatory factors that may contribute to the inflammatory process in RA. | Cadherin-11 regulates fibroblast inflammation.
Chang SK, Noss EH, Chen M, Gu Z, Townsend K, Grenha R, Leon L, Lee SY, Lee DM, Brenner MB., Free PMC Article | 07/30/2011 |
| Cdh2 and Cdh11 are crucial regulators of postnatal skeletal growth and bone mass maintenance, serving overlapping, yet distinct, functions in the osteogenic lineage. | N-cadherin and cadherin 11 modulate postnatal bone growth and osteoblast differentiation by distinct mechanisms.
Di Benedetto A, Watkins M, Grimston S, Salazar V, Donsante C, Mbalaviele G, Radice GL, Civitelli R., Free PMC Article | 01/29/2011 |
| Cdh11 acts as a tumor suppressor in a murine retinoblastoma model by facilitating tumor cell death | Cdh11 acts as a tumor suppressor in a murine retinoblastoma model by facilitating tumor cell death.
Marchong MN, Yurkowski C, Ma C, Spencer C, Pajovic S, Gallie BL., Free PMC Article | 08/16/2010 |
| fibroblast-like synoviocytes express both N-cadherin and cadherin 11, but they do not coimmunoprecipitate, suggesting these cadherins are not in the same molecular complex | Coexpression of two mesenchymal cadherins, cadherin 11 and N-cadherin, on murine fibroblast-like synoviocytes.
Agarwal SK, Lee DM, Kiener HP, Brenner MB. | 01/21/2010 |
| Results show that tendon formation in the developing limb requires precise regulation of cell shape via cadherin-11-mediated cell-cell junctions and coaxial alignment of plasma membrane channels in longitudinally stacked cells. | Tendon development requires regulation of cell condensation and cell shape via cadherin-11-mediated cell-cell junctions.
Richardson SH, Starborg T, Lu Y, Humphries SM, Meadows RS, Kadler KE., Free PMC Article | 01/21/2010 |
| the results show a link between Trio activity,Rac1 activation,neuronal organization,and recruitment of Cadherin-11 receptor to form a complex with Trio in hindbrain embryology. | Trio controls the mature organization of neuronal clusters in the hindbrain.
Backer S, Hidalgo-Sánchez M, Offner N, Portales-Casamar E, Debant A, Fort P, Gauthier-Rouvière C, Bloch-Gallego E., Free PMC Article | 01/21/2010 |
| synovial cadherin-11 determines the behavior of synovial cells in their proinflammatory and destructive tissue response in inflammatory arthritis | Cadherin-11 in synovial lining formation and pathology in arthritis.
Lee DM, Kiener HP, Agarwal SK, Noss EH, Watts GF, Chisaka O, Takeichi M, Brenner MB. | 01/21/2010 |
| A 2.62 Mbp minimal region of genomic loss of chromosome 16q22 was found in retinoblastoma which contains a hotspot CDH11, implicating CDH11as a potential tumor suppressor gene in retinoblastoma. | Minimal 16q genomic loss implicates cadherin-11 in retinoblastoma.
Marchong MN, Chen D, Corson TW, Lee C, Harmandayan M, Bowles E, Chen N, Gallie BL. | 01/21/2010 |
| Cdh11 in intercellular junctions interconnect dermal papilla cells in developing hair follicles and seem to be responsible for establishment of these junctions. | Establishment of cadherin-based intercellular junctions in the dermal papilla of the developing hair follicle.
Nanba D, Nakanishi Y, Hieda Y. | 01/21/2010 |
| Cadherin 11 expression initially appears in motor columns before extending to the whole spinal cord, dorsal root ganglia, and sensory-motor peripheral nerves; later, its expression decreases in nervous tissues and becomes predominant in mesenchymes. | Complementary expression and regulation of cadherins 6 and 11 during specific steps of motoneuron differentiation.
Marthiens V, Padilla F, Lambert M, Mege RM. | 01/21/2010 |
| Together, these studies implicate cadherin-11 in synovial tissue and lining layer formation and provide an in vitro system to model fibroblast-like synoviocyte behavior and function in organizing the synovial tissue. | Cadherin-11 induces rheumatoid arthritis fibroblast-like synoviocytes to form lining layers in vitro.
Kiener HP, Lee DM, Agarwal SK, Brenner MB., Free PMC Article | 01/21/2010 |
| cadherin-11 directly regulates the differentiation of mesenchymal cells into the cells of the osteo-lineage and the chondro-lineage in a different manner from N-cadherin | Cell-cell interaction mediated by cadherin-11 directly regulates the differentiation of mesenchymal cells into the cells of the osteo-lineage and the chondro-lineage.
Kii I, Amizuka N, Shimomura J, Saga Y, Kudo A. | 01/21/2010 |
| The cadherin-11 cytoplasmic juxtamembrane domain is a regulator of alpha-catenin turnover at adherens junctions and actin-cytoskeletal organization that is critical for intercellular motility and rearrangement in multicellular clusters. | The cadherin-11 cytoplasmic juxtamembrane domain promotes alpha-catenin turnover at adherens junctions and intercellular motility.
Kiener HP, Stipp CS, Allen PG, Higgins JM, Brenner MB., Free PMC Article | 01/21/2010 |
| Cadherin-11 enhanced axon growth and prevented interactions occurring between growing axons, providing evidence for a role of cadherin-11 in the control of growth cone progression. | A novel function for cadherin-11 in the regulation of motor axon elongation and fasciculation.
Marthiens V, Gavard J, Padilla F, Monnet C, Castellani V, Lambert M, Mège RM. | 01/21/2010 |