| REVIEW: current view of the interaction of PTEN with the plasma membrane and what the implications are for cancer biology | Regulation of PTEN function as a PIP3 gatekeeper through membrane interaction.
Vazquez F, Devreotes P. | 01/21/2010 |
| results confirm that PIK3CA mutations are frequent in endometrial carcinoma and support the hypothesis that PIK3CA mutations may have an additive effect to PTEN monoallelic inactivation in endometrial carcinoma | PIK3CA gene mutations in endometrial carcinoma: correlation with PTEN and K-RAS alterations.
Velasco A, Bussaglia E, Pallares J, Dolcet X, Llobet D, Encinas M, Llecha N, Palacios J, Prat J, Matias-Guiu X. | 01/21/2010 |
| Data show that UVB irradiation increases PTEN/Akt phosphorylation in dermal fibroblasts, and inhibition of PTEN and activation of Akt by phosphorylation are involved in UVB-induced MMP-1 and -3 secretions through upregulation of AP-1 activity. | Ultraviolet B-induced matrix metalloproteinase-1 and -3 secretions are mediated via PTEN/Akt pathway in human dermal fibroblasts.
Oh JH, Kim A, Park JM, Kim SH, Chung AS. | 01/21/2010 |
| Cooperation between this gene and BMPR1A gene is deleted on chromoome 10 in juvenile polyposis coli. | [Contiguous gene deletion within chromosome arm 10q is associated with juvenile polyposis of infancy, reflecting cooperation between the BMPR1A and PTEN tumor-suppressor genes].
Delnatte C, Sanlaville D, Mougenot JF, Stoppa-Lyonnet D. | 01/21/2010 |
| PTEN mutations were significantly correlated with uterine endometrioid carcinoma compared with atypical hyperplasia. | PIK3CA and PTEN mutations in uterine endometrioid carcinoma and complex atypical hyperplasia.
Hayes MP, Wang H, Espinal-Witter R, Douglas W, Solomon GJ, Baker SJ, Ellenson LH. | 01/21/2010 |
| PTEN/PI 3-kinase signaling and cyclin D1 control a novel pathway that regulates assembly of the SCF(SKP2) complex. | Regulation of SCF(SKP2) ubiquitin E3 ligase assembly and p27(KIP1) proteolysis by the PTEN pathway and cyclin D1.
Jonason JH, Gavrilova N, Wu M, Zhang H, Sun H. | 01/21/2010 |
| PPARgamma and RAR play an important role in controlling the growth of leukemia cells via the up-regulation of PTEN | Peroxisome proliferator-activated receptor gamma and retinoic acid receptor synergistically up-regulate the tumor suppressor PTEN in human promyeloid leukemia cells.
Lee YR, Yu HN, Noh EM, Kim JS, Song EK, Han MK, Kim BS, Lee SH, Park J. | 01/21/2010 |
| functional role of PTEN in the molecular pathogenesis of prostatic disease [review] | The role of PTEN in the progression and survival of prostate cancer.
Deocampo ND, Huang H, Tindall DJ. | 01/21/2010 |
| PTEN mutations are uncommon in Proteus syndrome | PTEN mutations are uncommon in Proteus syndrome.
Barker K, Martinez A, Wang R, Bevan S, Murday V, Shipley J, Houlston R, Harper J., Free PMC Article | 12/1/2001 |